Results 61 to 70 of about 326,099 (248)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Is pre-emptive classical biological control feasible for Aleurocanthus woglumi in Europe?

open access: yesBiological Control
Citrus blackfly, Aleurocanthus woglumi Ashby (Hemiptera: Aleyrodidae) is a major pest of Citrus spp that originated from south-east Asia and spread in many tropical and subtropical regions of the world. Citrus blackfly has not yet dispersed either in the
Panagiotis G. Milonas   +1 more
doaj   +1 more source

The effects of agent hybridization on the efficacy of biological control of tansy ragwort at high elevations

open access: yesEvolutionary Applications, 2019
The success rate of weed biological control programs is difficult to evaluate and the factors affecting it remain poorly understood. One aspect which is still unclear is whether releases of multiple, genetically distinct populations of a biological ...
Marianna Szűcs   +5 more
doaj   +1 more source

Hybridization and range expansion in tamarisk beetles (Diorhabda spp.) introduced to North America for classical biological control. [PDF]

open access: yesEvol Appl, 2022
Stahlke AR   +9 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

7 Classical biological control of plant pathogens

open access: yes, 1995
(Uploaded by Plazi for the IPBES Invasive Alien Species Assessment) Classical biological control, as shown by successful programmes against weeds and insects, offers considerable advantages over other control methods. It is reasonably permanent, has no harmful side effects, attack is limited to a very small group of related species, agents are self ...
Scott, John K.   +2 more
openaire   +3 more sources

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