Results 71 to 80 of about 8,745,456 (267)

Is the relativity principle consistent with electrodynamics? Towards a logico-empiricist reconstruction of a physical theory [PDF]

, 2009
It is common in the literature on electrodynamics and relativity theory that the transformation rules for the basic electrodynamical quantities are derived from the hypothesis that the relativity principle (RP) applies for Maxwell's electrodynamics.
Gomori, Marton, Szabo, Laszlo E.
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Quantum Gravity: Has Spacetime Quantum Properties? [PDF]

, 2009
The conceptual incompatibility between General Relativity and Quantum Mechanics is generally seen as a sufficient motivation for the development of a theory of Quantum Gravity. If - so a typical argumentation - Quantum Mechanics gives a universally valid
Hedrich, Reiner
core  

First-Order Logic Foundation of Relativity Theories [PDF]

, 2006
Motivation and perspective for an exciting new research direction interconnecting logic, spacetime theory, relativity--including such revolutionary areas as black hole physics, relativistic computers, new cosmology--are presented in this paper.
X. Madarasz, Judit, Nemeti, Istvan, Németi, I, Székely, G, Szekely, Gergely, Madarász, J   +5 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A No-Go Theorem About Rotation in Relativity Theory [PDF]

, 2000
Within the framework of general relativity, in some cases at least, it is a delicate and interesting question just what it means to say that an extended body is or is not "rotating". It is so for two reasons.
Malament, David B.
core  

Dynamical tidal response of Schwarzschild Black Holes

Journal of High Energy Physics
Dynamical Love numbers capture the conservative response of an object to a time-dependent external tidal gravitational field. We compute the dynamical Love numbers of Schwarzschild black holes in general relativity within a point-particle effective field
Oscar Combaluzier-Szteinsznaider, Daniel Glazer, Austin Joyce, Maria J. Rodriguez, Luca Santoni   +4 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source