Results 111 to 120 of about 574,752 (282)

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

open access: yesAdvanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob   +12 more
wiley   +1 more source

Quantum Logic as Classical Logic

open access: yes, 2014
We propose a semantic representation of the standard quantum logic QL within a classical, normal modal logic, and this via a lattice-embedding of orthomodular lattices into Boolean algebras with one modal operator. Thus our classical logic is a completion of the quantum logic QL.
openaire   +2 more sources

An Integrated NLP‐ML Framework for Property Prediction and Design of Steels

open access: yesAdvanced Science, EarlyView.
This study presents a data‐driven framework that uses language‐processing techniques to interpret steel processing descriptions and machine‐learning models to predict mechanical properties. By organising complex process histories into meaningful groups and enabling rapid property forecasts, the work supports faster, more informed steel design through ...
Kiran Devraju   +5 more
wiley   +1 more source

Adab-ı Sedat'taki Tartışma Örneklerinden Bazılarının Modern Mantık'taki Tartışma Mantığı Çizelgesi İçinde Uygulanması

open access: yesCumhuriyet Üniversitesi İlahiyat Fakültesi Dergisi, 2008
Bu makalenin amacı; 20. yüzyılın başı'anndan günümüze değin gelen klasik ve moçlern mantık çekişmelerinden sıyrılıp her iki mantık anla- . yı ş ının örtüşen noktalannın olup olmayacağını irdelemektir.
Necati DEMiR
doaj  

Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng   +18 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

open access: yesAdvanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

A real argument to defy classical logic

open access: yesPrincipia: An International Journal of Epistemology
In this paper, an argument by Fisher (2004) is formalized and evaluated by means of some tools of classical logic. The argument presented by Fisher is a version of a piece of reasoning of great historical importance known as Pascal’s Wager.
Héctor Hernández Ortiz
doaj   +1 more source

Polyelectrolyte Design Principles for Electrophoretic Drug Delivery

open access: yesAdvanced Science, EarlyView.
Structure–property–function mapping of polyelectrolytes reveals how composition and nanoscale order control on‐demand electrophoretic drug transport. Charge density quantified under implant‐relevant conditions shows that encapsulation limits swelling, enabling high effective charge density.
Helena Saarela Unemo   +8 more
wiley   +1 more source

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