Results 31 to 40 of about 2,307 (164)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A 4-vector formalism for classical mechanics

open access: yesRevista Brasileira de Ensino de Física
We present a matrix formalism, inspired by the Minkowski four-vectors of special relativity, useful to solve classical physics problems related to both mechanics and thermodynamics.
J. Güémez, M. Fiolhais
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Theoretical Physics: A Primer for Philosophers of Science

open access: yesPrincipia: An International Journal of Epistemology, 2009
We give a overview of the main areas in theoretical physics, with emphasis on their relation to Lagrangian formalism in classical mechanics. This review covers classical mechanics; the road from classical mechanics to Schrödinger’s quantum mechanics ...
Francisco Antonio Doria
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Classical Limit of Quantum Mechanics for Damped Driven Oscillatory Systems: Quantum–Classical Correspondence

open access: yesFrontiers in Physics, 2021
The investigation of quantum–classical correspondence may lead to gaining a deeper understanding of the classical limit of quantum theory. I have developed a quantum formalism on the basis of a linear invariant theorem, which gives an exact quantum ...
Jeong Ryeol Choi
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Classicalization of Quantum Mechanics: Classical Radiation Damping Without the Runaway Solution

open access: yesPhysics
In this paper, we review a new treatment of classical radiation damping, which resolves a known contradiction in the Abraham–Lorentz equation that has long been a concern. This radiation damping problem has already been solved in quantum mechanics by the
Tomio Petrosky   +2 more
doaj   +1 more source

A symplectic integrator for molecular dynamics on a hypersphere

open access: yesCondensed Matter Physics, 2020
We present a reversible and symplectic algorithm called ROLL, for integrating the equations of motion in molecular dynamics simulations of simple fluids on a hypersphere Sd of arbitrary dimension d. It is derived in the framework of geometric algebra and
J.-M. Caillol
doaj   +1 more source

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