Results 41 to 50 of about 571,812 (288)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Ergodic hypothesis in classical statistical mechanics

Revista Brasileira de Ensino de Física
An updated discussion on physical and mathematical aspects of the ergodic hypothesis in classical equilibrium statistical mechanics is presented. Then a practical attitude for the justification of the microcanonical ensemble is indicated.
César R. de Oliveira, Thiago Werlang
doaj   +1 more source

Infinite motion in the classical functional mechanics

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2013
In the paper the description of infinite movement in the functional formulation of classical mechanics is investigated. On the example of simple exactly solvable problems (passing through the barrier and falling in the center) the two classes of problems
Andrey Igorevich Mikhailov
doaj   +1 more source

Classical mechanics is not h=0 limit of quantum mechanics

, 2004
Both the set of quantum states and the set of classical states described by symplectic tomographic probability distributions (tomograms) are studied. It is shown that the sets have common part but there exist tomograms of classical states which are not ...
Man'ko, O. V., Man'ko, V. I.
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A 4-vector formalism for classical mechanics

Revista Brasileira de Ensino de Física
We present a matrix formalism, inspired by the Minkowski four-vectors of special relativity, useful to solve classical physics problems related to both mechanics and thermodynamics.
J. Güémez, M. Fiolhais
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

The Possibility of Reconciling Quantum Mechanics with Classical Probability Theory

, 2007
We describe a scheme for constructing quantum mechanics in which a quantum system is considered as a collection of open classical subsystems. This allows using the formal classical logic and classical probability theory in quantum mechanics. Our approach
A. N. Kolmogorov, D. A. Slavnov, D. A. Slavnov, D. A. Slavnov, G. G. Emch, J. Dixmier, J. F. Clauser, J. Neumann von, J. Neveu, J. S. Bell, M. A. Neimark, M. Born, P. Jordan, S. Kochen, W. Rudin   +14 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Theoretical Physics: A Primer for Philosophers of Science

Principia: An International Journal of Epistemology, 2009
We give a overview of the main areas in theoretical physics, with emphasis on their relation to Lagrangian formalism in classical mechanics. This review covers classical mechanics; the road from classical mechanics to Schrödinger’s quantum mechanics ...
Francisco Antonio Doria
doaj