Results 71 to 80 of about 48,047 (254)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Path Integrals for (Complex) Classical and Quantum Mechanics

open access: yesActa Polytechnica, 2011
An analysis of classical mechanics in a complex extension of phase space shows that a particle in such a space can behave in a way redolent of quantum mechanics; additional dimensions permit ‘tunnelling’ without recourse to instantons and time/energy ...
R. J. Rivers
doaj  

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Two helpful developments towards better understanding of adiabatic invariance in classical mechanics

open access: yesRevista Brasileira de Ensino de Física
The topic of difficult understanding of adiabatic invariance in classical mechanics is dealt with in a more understandable way. Using the one-dimensional harmonic oscillator as an example, the goals of this paper are twofold.
J.R. Mohallem
doaj   +1 more source

High-performance combinatorial optimization based on classical mechanics. [PDF]

open access: yesSci Adv, 2021
Goto H   +8 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Assessment of Classical Force-Fields for Graphene Mechanics

open access: yesCrystals
The unique properties of graphene have attracted the interest of researchers from various fields, and the discovery of graphene has sparked a revolution in materials science, specifically in the field of two-dimensional materials.
Zhiwei Ma   +7 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

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