Results 71 to 80 of about 582,209 (274)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Czy możemy wykazać istnienie zjawisk całkowicie przypadkowych?

open access: yesZagadnienia Filozoficzne w Nauce, 2018
I show how classical and quantum physics approach the problem of randomness and probability. Contrary to popular opinions, neither we can prove that classical mechanics is a deterministic theory, nor that quantum mechanics is a nondeterministic one.
Marek Kuś
doaj  

Generalized Uncertainty Principle, Classical Mechanics, and General Relativity

open access: yesPhysics Letters B, 2020
The Generalized Uncertainty Principle (GUP) has been directly applied to the motion of (macroscopic) test bodies on a given space-time in order to compute corrections to the classical orbits predicted in Newtonian Mechanics or General Relativity.
Roberto Casadio, Fabio Scardigli
doaj   +1 more source

A Quantum is a Complex Structure on Classical Phase Space

open access: yes, 2004
Duality transformations within the quantum mechanics of a finite number of degrees of freedom can be regarded as the dependence of the notion of a quantum, i.e., an elementary excitation of the vacuum, on the observer on classical phase space.
Dubois–Violette M.   +6 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The Formulations of Classical Mechanics with Foucault’s Pendulum

open access: yesPhysics, 2020
Since the pioneering works of Newton (1643–1727), mechanics has been constantly reinventing itself: reformulated in particular by Lagrange (1736–1813) then Hamilton (1805–1865), it now offers powerful conceptual and mathematical tools for the exploration
Nicolas Boulanger, Fabien Buisseret
doaj   +1 more source

Classical Mechanics

open access: yes, 2005
An overview of the foundations of Classical ...
Gallavotti, Giovanni
core  

Star Products and Geometric Algebra

open access: yes, 2004
The formalism of geometric algebra can be described as deformed super analysis. The deformation is done with a fermionic star product, that arises from deformation quantization of pseudoclassical mechanics.
Allen C. Hirshfeld   +20 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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