Results 51 to 60 of about 4,376,819 (306)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Hybrid Classical-Quantum Computing: Applications to Statistical Mechanics of Neocortical Interactions [PDF]
, 2021 Several commerical quantum computers are now available that offer Hybrid Classical-Quantum computing Application is made to a classical-quantum model of human neocortex Statistical Mechanics of Neocortical Interactions SMNI which has had its ...
Lester Ingber
core
Condensed Matter Physics, 2018 A simple ansatz for the study of velocity autocorrelation functions in fluids at different timescales is proposed. The ansatz is based on an effective summation of the infinite continued fraction at a reasonable assumption about convergence of relaxation
V.V. Ignatyuk, I.M. Mryglod, T. Bryk
doaj +1 more source
Dynamical Temperature from the Phase Space Trajectory
Hungarian Journal of Industry and Chemistry, 2017 In classical statistical mechanics the trajectory in phase space represents the propagation of a classical Hamiltonian system. While trajectories play a key role in chaotic system theory, exploitation of a single trajectory has yet to be considered. This
Baranyai András
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Between classical and quantum [PDF]
, 2005 The relationship between classical and quantum theory is of central importance to the philosophy of physics, and any interpretation of quantum mechanics has to clarify it.
Landsman, Nicolaas P.
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
What is Statistical Mechanics? [PDF]
, 2012 Thermodynamics describes a large class of phenomena we observe in macroscopic systems. The aim of statistical mechanics is to account for this behaviour in terms of the dynamical laws governing the microscopic constituents of macroscopic systems and ...
Frigg, Roman
core
Gibbs’ Paradox in the Light of Newton’s Notion of State
Entropy, 2009 In this letter, it is argued that the correct counting of microstates is obtained from the very beginning when using Newtonian rather than Laplacian state functions, because the former are intrinsically permutation invariant.
Peter Enders
doaj +1 more source