Results 61 to 70 of about 4,388,061 (261)
Dynamical Temperature from the Phase Space Trajectory
Hungarian Journal of Industry and Chemistry, 2017 In classical statistical mechanics the trajectory in phase space represents the propagation of a classical Hamiltonian system. While trajectories play a key role in chaotic system theory, exploitation of a single trajectory has yet to be considered. This
Baranyai András
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
What is Statistical Mechanics? [PDF]
, 2012 Thermodynamics describes a large class of phenomena we observe in macroscopic systems. The aim of statistical mechanics is to account for this behaviour in terms of the dynamical laws governing the microscopic constituents of macroscopic systems and ...
Frigg, Roman
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Gibbs’ Paradox in the Light of Newton’s Notion of State
Entropy, 2009 In this letter, it is argued that the correct counting of microstates is obtained from the very beginning when using Newtonian rather than Laplacian state functions, because the former are intrinsically permutation invariant.
Peter Enders
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
On Symmetry and Conserved Quantities in Classical Mechanics [PDF]
, 2005 This paper expounds the relations between continuous symmetries and conserved quantities, i.e. Noether's ``first theorem'', in both the Lagrangian and Hamiltonian frameworks for classical mechanics.
Butterfield, Jeremy
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Brussels-Austin Nonequilibrium Statistical Mechanics in the Later Years: Large Poincaré Systems and Rigged Hilbert Space [PDF]
, 2003 This second part of a two-part essay discusses recent developments in the Brussels-Austin Group after the mid 1980s. The fundamental concerns are the same as in their similarity transformation approach (see Part I), but the contemporary approach utilizes
Bishop, Robert
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