Results 61 to 70 of about 4,376,819 (306)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
On Symmetry and Conserved Quantities in Classical Mechanics [PDF]
, 2005 This paper expounds the relations between continuous symmetries and conserved quantities, i.e. Noether's ``first theorem'', in both the Lagrangian and Hamiltonian frameworks for classical mechanics.
Butterfield, Jeremy
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Brussels-Austin Nonequilibrium Statistical Mechanics in the Later Years: Large Poincaré Systems and Rigged Hilbert Space [PDF]
, 2003 This second part of a two-part essay discusses recent developments in the Brussels-Austin Group after the mid 1980s. The fundamental concerns are the same as in their similarity transformation approach (see Part I), but the contemporary approach utilizes
Bishop, Robert
core
A Direct Method for the Analyticity of the Pressure for Certain Classical Unbounded Models
Advances in Mathematical Physics, 2011 The goal of this paper is to provide estimates leading to a direct proof of the analyticity of the pressure for certain classical unbounded models. We use our new formula (Lo, 2007) to establish the analyticity of the pressure in the thermodynamic limit ...
Assane Lo
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Measurement and Classical Regime in Quantum Mechanics [PDF]
, 2011 This article (for the Oxford Handbook of Philosophy of Physics) focuses on two of the main problems raising interpretational issues in quantum mechanics, namely the notorious measurement problem and the equally important but not quite as widely discussed
Guido Bacciagaluppi +1 more
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Closed Trans-Scale Statistical Microdamage Mechanics [PDF]
, 2002 Damage and failure due to distributed microcracks or microvoids are on the challenging frontiers of solid mechanics. This appeals strongly to tools not yet fully developed in continuum damage mechanics, in particular to irreversible statistical ...
李晖凌 +4 more
core +2 more sources
Admitting Spontaneous Violations of the Second Law in Continuum Thermomechanics
Entropy, 2017 We survey new extensions of continuum mechanics incorporating spontaneous violations of the Second Law (SL), which involve the viscous flow and heat conduction.
Martin Ostoja-Starzewski
doaj +1 more source