Results 81 to 90 of about 4,376,819 (306)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Deformation quantization: Quantum mechanics lives and works in phase space

open access: yesEPJ Web of Conferences, 2014
Wigner’s 1932 quasi-probability Distribution Function in phase-space, his first paper in English, is a special (Weyl) representation of the density matrix.
Zachos Cosmas K.
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Compendium of the foundations of classical statistical physics [PDF]

open access: yes, 2006
Roughly speaking, classical statistical physics is the branch of theoretical physics that aims to account for the thermal behaviour of macroscopic bodies in terms of a classical mechanical model of their microscopic constituents, with the help of ...
Uffink, Jos
core  

Contact Hamiltonian Dynamics: The Concept and Its Use

open access: yesEntropy, 2017
We give a short survey on the concept of contact Hamiltonian dynamics and its use in several areas of physics, namely reversible and irreversible thermodynamics, statistical physics and classical mechanics.
Alessandro Bravetti
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Variational Methods for Nonsmooth Mechanics [PDF]

open access: yes, 2003
In this thesis we investigate nonsmooth classical and continuum mechanics and its discretizations by means of variational numerical and geometric methods.
Fetecau, Razvan Constantin
core   +1 more source

A Correspondence Principle

open access: yesSubstantia, 2018
A single mathematical theme underpins disparate physical phenomena in classical, quantum and statistical mechanical contexts. This mathematical “correspondence principle”, a kind of wave–particle duality with glorious realizations in classical and modern
Barry D. Hughes, Barry W. Ninham
doaj   +1 more source

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