Results 61 to 70 of about 14,260,147 (248)
"The Old Vines Are Buried Deep": Classical Motifs in John Frankenheimer's Seconds
, 2015 John Frankenheimer's Seconds (1966) is the story of a middle-aged banker who abandons family and career, purchasing from the secretive Company a new identity, vocation and surgically altered youthful appearance.
Easton, Seán;
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Theoretical Roman Archaeology JournalThis is a review of Interamna Lirenas: A Roman town in Central Italy revealed by Alessandro Launaro and Martin Millett, published in 2023 by the McDonald Institute for Archaeological Research.
Allison Smith
doaj +2 more sources
Are We There Yet? Archaeology and the Postmodern in the New Millennium
Current Swedish Archaeology, 2012 The present text discusses the significance of the post- modern condition in contemporary archaeology. Five themes associated with postmodernism are discussed (a) the relativization of truth, knowledge, and mean- ing, (b) the fragmentation of the ...
Fredrik Fahlander
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Divine Appearance 0f Härn: Determining the Identity of a Bronze Age Metal Hoard
Current Swedish Archaeology, 2010 This article aims to investigate the mysterious divinity Härn on the basis of a Bronze Age metal hoard from Härnevi in Uppland. The premise is that this hoard rep- resents a cultural category that reflects a divine concept that must be investigated in ...
Magdalena Forsgren
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The Journal of Classics TeachingPlaying is connected at a deep level to how we learn, participate in and create culture, as it is dynamic, complex and even unpredictable just as learning is (Reinhardt, 2019). Even Plato in his Theaetetus recognises the importance of such a component in
Irene Di Gioia
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source