Results 71 to 80 of about 14,260,147 (248)
This text discusses reuse and modifications of older graves in southern Sweden during the Late Iron Age and early medieval period (c. 9th to 12th centu- ries AD).
Fredrik Fahlander
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Illinois Classical Studies v.21 1996 [PDF]
Submitted by Sarah Shreeves (sshreeve@illinois.edu) on 2009-07-09T14:32:23Z No. of bitstreams: 1 illinoisclassica211996univ_bw.pdf: 7735297 bytes, checksum: d36fa065f2ee9e945751db2c8adcb823 (MD5)Made available in DSpace on 2009-07-09T14:32:23Z (GMT). No.
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The Evolutionary History of the Extinct Baltic Sea Harp Seal Population
The now‐extinct harp seal population that inhabited the Baltic Sea from the Mesolithic to the Iron Age is an enigma. It occurred outside the species' contemporary Arctic range, likely deviated from typical harp seal migratory behaviour, and experienced ...
Maiken Hemme Bro‐Jørgensen +7 more
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Borderland-stalkers and Stalking-horses Horse Sacrifice as Liminal Activity in the Early Iron Age
This paper investigates the fact that many Early Iron Age wetland sacrifices were deliberately placed in liminal zones. The sacrifice of horses as well as the manipulation of their heads, hoofs and tails turned them into liminal creatures.
Anne Monikander
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

