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CRISPR/Cas9-mediated knockout of STAT1 in porcine-derived cell lines to elucidate the role of STAT1 in autophagy following classical swine fever virus infection. [PDF]

Front Immunol
Zhang L, Liang D, Min K, Liang J, Tian Y, Liu C, Luo TR, Li X.   +7 more
europepmc   +1 more source

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Evidence of natural recombination in classical swine fever virus

Virus Research, 2007
Classical swine fever (CSF) virus, one member of the family Flaviviridae is the pathogen of CSF, an economically important and highly contagious disease of pigs. Although homologous recombination has been demonstrated in many other members of the family, it is unknown whether there is recombination in natural populations of CSFV.
Cheng-Qiang He, Nai-Zheng Ding
exaly   +3 more sources

Vaccination influences the evolution of classical swine fever virus

Infection, Genetics and Evolution, 2014
Classical swine fever is a serious, economically damaging disease caused by classical swine fever virus (CSFV). The CSFV is composed of two clades, according to phylogenetic estimates. Attenuated live vaccine such as HCLV, has been widely used to protect pigs from CSFV, but the influence of vaccination on the evolution of CSFV has not been studied.
Wei Ji, Hong-Li Si, Nai-Zheng Ding
exaly   +3 more sources

Genetic typing of classical swine fever virus

Veterinary Microbiology, 2000
Three regions of the classical swine fever virus (CSFV) genome that have been widely sequenced were compared with respect to their ability to discriminate between isolates and to segregate viruses into genetic groups. Sequence data-sets were assembled for 55 CSFVs comprising 150 nucleotides of the 5' non-translated region, 190 nucleotides of the E2 ...
D J Paton, I Greiser-Wilke, Tomasz Stadejek   +2 more
exaly   +3 more sources

Genetic variability of classical swine fever virus

Virus Research, 1996
The genetic variability of classical swine fever virus was studied by comparative nucleotide sequence analysis of 76 virus isolates, collected during a half century from three continents. Parts of the E2 (gp55) and the polymerase gene coding regions of the viral genome were amplified by RT-PCR and DNA fragments of 254 and 207 bp, respectively, were ...
S, Vilcek, T, Stadejek, A, Ballagi-Pordány, J P, Lowings, D J, Paton, S, Belák   +5 more
openaire   +2 more sources

Classical Swine Fever Virus

2020
Classical swine fever virus (CSFV), belonging to the genus Pestivirus of the family Flaviviridae and species Pestivirus C, is the aetiological agent of a disease called classical swine fever (CSF) or hog cholera, which is a devastating transboundary disease of pigs across the globe.
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Emergence of classical swine fever virus in Israel in 2009

The Veterinary Journal, 2011
Classical swine fever (CSF) re-emerged in Israel in February 2009 after an absence of 62 years. The outbreak occurred on a domestic pig farm in northern Israel and affected domestic pigs and wild boar. On the basis of phylogenetic analysis of a 190 base pair fragment of the E2 glycoprotein gene, the Israeli CSF virus strain belonged to genotype 2.1 and
D, David, N, Edri, B A, Yakobson, V, Bombarov, R, King, I, Davidson, P, Pozzi, Y, Hadani, M, Bellaiche, S, Schmeiser, S, Perl   +10 more
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Transmission of classical swine fever virus by artificial insemination

Veterinary Microbiology, 1999
Classical swine fever (CSF) virus was introduced into an artificial insemination centre during the CSF epizootic of 1997-1998 in the Netherlands. The risk of further spread of CSF virus via contaminated semen was recognised, but could not be assessed because scientific data on this issue were not available.
de Smit, A.J., Bouma, A., Terpstra, C., van Oirschot, J.T.   +3 more
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Survival and inactivation of classical swine fever virus

Veterinary Microbiology, 2000
Classical swine fever virus, like many enveloped viruses, may be regarded as moderately fragile. It shows a short but variable survival time in the environment, depending on physical conditions, but may remain viable for prolonged periods in favourable circumstances as found, for example, in stored meat.
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Phylogenetic comparison of classical swine fever virus in China

Virus Research, 2001
An N-terminal fragment of the E2 gene of classical swine fever (CSF) virus encoding major immunogenic sites was amplified by RT-PCR directly from 110 clinical specimens representing 109 epizootic sites during the last decade in China. Phylogenetic relationships between these viruses as well as 20 reference strains were determined by comparison of their
C, Tu, Z, Lu, H, Li, X, Yu, X, Liu, Y, Li, H, Zhang, Z, Yin   +7 more
openaire   +2 more sources