Interactome between ASFV and host immune pathway proteins
mSystems, 2023 African swine fever virus (ASFV) causes severe acute hemorrhagic disease with high mortality in domestic pigs but minimal or no symptoms to warthogs, for which the underlying mechanism remains elusive.
Qijun Wu +13 more
doaj +3 more sources
ASFV-G-∆I177L as an Effective Oral Nasal Vaccine against the Eurasia Strain of Africa Swine Fever
Viruses, 2021 The African swine fever virus (ASFV) is currently causing a pandemic affecting wild and domestic swine from Western Europe to Asia. No commercial vaccines are available to prevent African swine fever (ASF), resulting in overwhelming economic losses to ...
Elizabeth Ramirez-Medina +2 more
exaly +3 more sources
ASFV Gene A151R Is Involved in the Process of Virulence in Domestic Swine
Viruses, 2022 African swine fever virus (ASFV) is the etiological agent of a swine pandemic affecting a large geographical area extending from Central Europe to Asia. The viral disease was also recently identified in the Dominican Republic and Haiti.
Elizabeth Ramirez-Medina +2 more
exaly +3 more sources
Viruses, 2023 ASFV vaccine candidate ASFV-G-ΔI177L has been shown to be highly efficacious in inducing protection against challenges with the parental virus, the Georgia 2010 isolate, as well as against field strains isolated from Vietnam. ASFV-G-ΔI177L has been shown
Elizabeth Ramirez-Medina +2 more
exaly +3 more sources
The deletion of the EP402R and MGF505/360 genes attenuates a genotype I/II recombinant ASFV but fails to confer complete protection against homologous or genotype II challenge in pigs [PDF]
Emerging Microbes and InfectionsAfrican swine fever (ASF), a pig disease caused by ASFV, is highly contagious and often lethal. The recent emergence of novel ASFV with I/II genomic recombination has posed significant challenges to global ASF prevention and control.
Yao Li +14 more
doaj +2 more sources
A review of some important viral diseases of wild boars [PDF]
Biotechnology in Animal Husbandry, 2021 Wild boars are one of the widest-ranging mammals worldwide and represent reservoirs for many important viruses. Disease outbreaks in domestic swine are often described as a consequence of contact with wild boars, and traditional rearing conditions are a ...
Nišavić Jakov +6 more
doaj +1 more source
Expression of a recombinant ASFV P30 protein and production of monoclonal antibodies
Open Veterinary Journal, 2023 Background: African Swine Fever (ASF) is an infectious disease that affects domestic pig and wild boar populations. The African Swine Fever Virus (ASFV) has a genome characterized by a very complex DNA (170-193 kb) that encodes for more than 200 ...
Rosrio Liberti +10 more
doaj +1 more source
Inhibition of African swine fever virus replication by β-glucan
Open Veterinary Journal, 2022 Background: African swine fever (ASF) is one of the most important diseases in pigs because of its effects on all ages and breeds. To date, the commercial vaccines and drugs for prevention of ASF are lacking in the market and the survival of ASFV in ...
Truong Anh Duc +10 more
doaj +1 more source
ASF -survivors’ sera do not inhibit African swine fever virus replication in vitro
Journal of Veterinary Research, 2022 African swine fever virus (ASFV) causes one of the most dangerous diseases of pigs and wild boar – African swine fever (ASF). Since its second introduction into Europe (in 2007), the disease has been spreading consistently, and now ASF-free European ...
Walczak Marek +4 more
doaj +1 more source
Novel mechanism of African swine fever virus protein regulating typeⅡinterferon signaling pathway
生物医学转化, 2022 African swine fever virus (ASFV) is a large DNA virus that is highly contagious and pathogenic in domestic pigs with a mortality rate up to 100%. However, how ASFV suppresses JAK-STAT1 signaling to evade the immune response remains unclear. In this study,
Zhang Jing, Li Dan, Zheng Haixue
doaj +1 more source