Results 21 to 30 of about 11,516 (233)

ASFV pA151R Negatively Regulates Type I IFN Production via Degrading E3 Ligase TRAF6

open access: yesFrontiers in Immunology
African swine fever (ASF) caused by African swine fever virus (ASFV) is a highly mortal and hemorrhagic infectious disease in pigs. Previous studies have indicated that ASFV modulates interferon (IFN) production.
Wen-Hai Feng   +2 more
exaly   +2 more sources

ASFV complete genomes sequences alignment

open access: yes, 2020
ASFV complete genomes sequences ...
Karalyan Zaven   +2 more
core   +3 more sources

Reclassification of ASFV into 7 Biotypes Using Unsupervised Machine Learning

open access: yesViruses, 2023
In 2007, an outbreak of African swine fever (ASF), a deadly disease of domestic swine and wild boar caused by the African swine fever virus (ASFV), occurred in Georgia and has since spread globally.
Mark Dinhobl   +8 more
semanticscholar   +4 more sources

The African Swine Fever Isolate ASFV-Kenya-IX-1033 Is Highly Virulent and Stable after Propagation in the Wild Boar Cell Line WSL [PDF]

open access: yesViruses, 2022
We describe the characterization of an African swine fever genotype IX virus (ASFV-Kenya-IX-1033), which was isolated from a domestic pig in western Kenya during a reported outbreak. This includes the efficiency of virus replication and in vivo virulence,
Johanneke Dinie Hemmink   +10 more
semanticscholar   +2 more sources

An Intracellular Epitope of ASFV CD2v Protein Elicits Humoral and Cellular Immune Responses

open access: yesAnimals, 2023
Simple Summary African swine fever (ASF) causes acute hemorrhagic disease in domestic pigs. This disease causes huge economic losses worldwide, and there are no safe and effective vaccines. The ASF virus (ASFV) has at least 68 structural proteins. One of
Wen-Long Lu   +11 more
semanticscholar   +2 more sources

Evaluation of the Function of the ASFV KP177R Gene, Encoding for Structural Protein p22, in the Process of Virus Replication and in Swine Virulence

open access: yesViruses, 2021
African swine fever virus (ASFV) causes a devastating disease of swine that has caused outbreaks in Central Europe since 2007, spreading into Asia in 2018.
Elizabeth A. Vuono   +7 more
doaj   +2 more sources

Deletion of the EP402R Gene from the Genome of African Swine Fever Vaccine Strain ASFV-G-∆I177L Provides the Potential Capability of Differentiating between Infected and Vaccinated Animals

open access: yesViruses
The African swine fever virus (ASFV) mutant ASFV-G-∆I177L is a safe and efficacious vaccine which induces protection against the challenge of its parental virus, the Georgia 2010 isolate.
M. Borca   +13 more
semanticscholar   +2 more sources

Deletion of the CD2v Gene from the Genome of ASFV-Kenya-IX-1033 Partially Reduces Virulence and Induces Protection in Pigs [PDF]

open access: yesViruses, 2022
Infection of pigs with the African swine fever virus (ASFV) leads to a devastating hemorrhagic disease with a high mortality of up to 100%. In this study, a CD2v gene deletion was introduced to a genotype IX virus from East Africa, ASFV-Kenya-IX-1033 ...
Johanneke Dinie Hemmink   +10 more
semanticscholar   +3 more sources

Effects of the NF-κB Signaling Pathway Inhibitor BAY11-7082 in the Replication of ASFV

open access: yesViruses, 2022
African swine fever virus (ASFV) mainly infects the monocyte/macrophage lineage of pigs and regulates the production of cytokines that influence host immune responses. Several studies have reported changes in cytokine production after infection with ASFV,
Qi Gao   +12 more
semanticscholar   +2 more sources

Towards an Original Anti-ASFV Vaccine: Cellular Immunity Induced by Extracellular Vesicles Engineered with ASFV Proteins

open access: yesVaccines
Background/Objectives: African Swine Fever (ASF) represents one of the most serious threats to animal health and global food security. The causative agent of ASF is the African swine fever virus (ASFV), a DNA virus belonging to the Asfarviridae family ...
Flavia Ferrantelli   +11 more
core   +3 more sources

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