Results 41 to 50 of about 5,108 (173)

Cellular immunity in ASFV responses

Virus Research, 2013
African swine fever virus (ASFV) infection usually results in an acute haemorrhagic disease with a mortality rate approaching 100% in domestic pigs. However, pigs can survive infection with less-virulent isolates of ASFV and may become chronically infected.
Haru-Hisa, Takamatsu, Michael S, Denyer, Anna, Lacasta, Catrina M A, Stirling, Jordi M, Argilaguet, Christopher L, Netherton, Chris A L, Oura, Carlos, Martins, Fernando, Rodríguez   +8 more
openaire   +2 more sources

The MGF360-16R ORF of African Swine Fever Virus Strain Georgia Encodes for a Nonessential Gene That Interacts with Host Proteins SERTAD3 and SDCBP

Viruses, 2020
African swine fever virus (ASFV) causes a contagious and frequently lethal disease of pigs with significant economic consequences to the swine industry.
Elizabeth Ramírez-Medina, Elizabeth A. Vuono, Lauro Velazquez-Salinas, Ediane Silva, Ayushi Rai, Sarah Pruitt, Keith A. Berggren, James Zhu, Manuel V. Borca, Douglas P. Gladue   +9 more
doaj   +1 more source

Marine fungal metabolites as antiviral agents: Computer-aided drug screening for selective inhibition of African swine fever virus dUTPase [PDF]

BioImpacts
Introduction: African swine fever (ASF) continues to be a significant threat to the global livestock industry due to its severe impact on pig populations. Currently, there are no approved therapeutic agents for the virus, and biosecurity measures such as
Mark Andrian B. Macalalad, Fredmoore L. Orosco   +1 more
doaj   +1 more source

Evaluation of an ASFV RNA Helicase Gene A859L for Virus Replication and Swine Virulence

Viruses, 2021
African swine fever virus (ASFV) is producing a devastating pandemic that, since 2007, has spread to a contiguous geographical area from central Europe to Asia. In July 2021, ASFV was detected in the Dominican Republic, the first report of the disease in
Elizabeth Ramirez-Medina, Elizabeth A. Vuono, Sarah Pruitt, Ayushi Rai, Nallely Espinoza, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +7 more
doaj   +1 more source

X69R Is a Non-Essential Gene That, When Deleted from African Swine Fever, Does Not Affect Virulence in Swine

Viruses, 2020
African swine fever virus (ASFV) is currently causing devastating outbreaks in Asia and Europe, and the ASFV strain Georgia (ASFV-G) is responsible for these outbreaks.
Elizabeth Ramirez-Medina, Elizabeth Vuono, Sarah Pruitt, Ayushi Rai, Ediane Silva, James Zhu, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +8 more
doaj   +1 more source

Insights into the function of ESCRT complex and LBPA in ASFV infection

Frontiers in Cellular and Infection Microbiology, 2023
The African swine fever virus (ASFV) is strongly dependent on an intact endocytic pathway and a certain cellular membrane remodeling for infection, possibly regulated by the endosomal sorting complexes required for transport (ESCRT). The ESCRT machinery is mainly involved in the coordination of membrane dynamics; hence, several viruses exploit this ...
Barrado-Gil, Lucía, García-Dorival, Isabel, Galindo Barreales, Inmaculada, Alonso Martí, Covadonga, Cuesta-Geijo, Miguel Ángel   +4 more
openaire   +4 more sources

Evaluation in Swine of a Recombinant Georgia 2010 African Swine Fever Virus Lacking the I8L Gene

Viruses, 2020
African swine fever virus (ASFV) is the causative agent of African swine fever, a disease currently causing significant economic losses in Europe and Asia. Specifically, the highly virulent ASFV strain Georgia 2010 (ASFV-G) is producing disease outbreaks
Elizabeth Vuono, Elizabeth Ramirez-Medina, Sarah Pruitt, Ayushi Rai, Ediane Silva, Nallely Espinoza, James Zhu, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +9 more
doaj   +1 more source

Modelling and stability analysis of ASFV with swill and the virus in the environment

Mathematical Biosciences and Engineering, 2022
<abstract><p>African swine fever (ASF) is an acute, hemorrhagic and severe infectious disease caused by the African swine fever virus (ASFV), and leads to a serious threat to the pig industry in China. Yet the impact of the virus in the environment and contaminated swill on the ASFV transmission is unclear in China.
Haitao Song, Lirong Guo, Zhen Jin, Shengqiang Liu   +3 more
openaire   +3 more sources

African swine fever virus – persistence in different environmental conditions and the possibility of its indirect transmission

Journal of Veterinary Research, 2019
Since 2007, African swine fever (ASF) has posed a serious threat to the European swine industry. In Poland, the numbers of reported outbreaks in pigs and affected areas grow every year.
Mazur-Panasiuk Natalia, Żmudzki Jacek, Woźniakowski Grzegorz   +2 more
doaj   +1 more source

Evaluation of the Function of the ASFV KP177R Gene, Encoding for Structural Protein p22, in the Process of Virus Replication and in Swine Virulence

Viruses, 2021
African swine fever virus (ASFV) causes a devastating disease of swine that has caused outbreaks in Central Europe since 2007, spreading into Asia in 2018.
Elizabeth A. Vuono, Elizabeth Ramirez-Medina, Sarah Pruitt, Ayushi Rai, Nallely Espinoza, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +7 more
doaj   +1 more source