Results 41 to 50 of about 11,516 (233)

Analysis of the Clinical Course of Experimental Infection with Highly Pathogenic African Swine Fever Strain, Isolated from an Outbreak in Poland. Aspects Related to the Disease Suspicion at the Farm Level

Pathogens, 2020
This paper was aimed to characterize clinical signs and pathomorphological lesions in twenty-two pigs, infected intranasally by different doses of African swine fever virus (Pol18_28298_O111), isolated during the outbreak in a pig farm that occurred in ...
Marek Walczak, Jacek Żmudzki, Natalia Mazur-Panasiuk, Małgorzata Juszkiewicz, Grzegorz Woźniakowski   +4 more
doaj   +1 more source

ASF -survivors’ sera do not inhibit African swine fever virus replication in vitro

Journal of Veterinary Research, 2022
African swine fever virus (ASFV) causes one of the most dangerous diseases of pigs and wild boar – African swine fever (ASF). Since its second introduction into Europe (in 2007), the disease has been spreading consistently, and now ASF-free European ...
Walczak Marek, Juszkiewicz Małgorzata, Szymankiewicz Krzesimir, Szczotka-Bochniarz Anna, Woźniakowski Grzegorz   +4 more
doaj   +1 more source

Assessment of African swine fever vaccine candidate ASFV-G-∆MGF in a reversion to virulence study

npj Vaccines, 2023
African swine fever (ASF) has gained panzootic dimensions and commercial vaccines are still unavailable. Recently, a series of live attenuated vaccines has raised hope for an efficacious and safe vaccine, among them “ASFV-G-∆MGF”. We tested the latter in
P. Deutschmann, J. Forth, J. Sehl-Ewert, T. Carrau, E. Viaplana, Jose Carlos Mancera, A. Urniza, M. Beer, S. Blome   +8 more
semanticscholar   +1 more source

Novel mechanism of African swine fever virus protein regulating typeⅡinterferon signaling pathway

生物医学转化, 2022
African swine fever virus (ASFV) is a large DNA virus that is highly contagious and pathogenic in domestic pigs with a mortality rate up to 100%. However, how ASFV suppresses JAK-STAT1 signaling to evade the immune response remains unclear. In this study,
Zhang Jing, Li Dan, Zheng Haixue
doaj   +1 more source

Comparison of Macrophage Responses to African Swine Fever Viruses Reveals that the NH/P68 Strain is Associated with Enhanced Sensitivity to Type I IFN and Cytokine Responses from Classically Activated Macrophages

Pathogens, 2020
African swine fever (ASF) poses a severe threat to the global pig industry for which currently there is no available vaccine. The aetiological ASF virus (ASFV) has a predilection for cells of the myeloid lineage, however little is known about its ...
Giulia Franzoni, Elisabetta Razzuoli, Silvia Dei Giudici, Tania Carta, Grazia Galleri, Susanna Zinellu, Mauro Ledda, Pierpaolo Angioi, Paola Modesto, Simon P. Graham, Annalisa Oggiano   +10 more
doaj   +1 more source

Identification of a new cell-penetrating peptide derived from the african swine fever virus CD2v protein

Drug Delivery, 2021
The African swine fever virus (ASFV) is a huge and complex DNA virus that can lead to the acute death of pigs and cause huge losses to the global swine industry.
Shunli Yang, Xinming Zhang, Yuying Cao, Shuo Li, Junjun Shao, Shiqi Sun, Huichen Guo, Shuanghui Yin   +7 more
doaj   +1 more source

ASF Vaccine Candidate ASFV-G-∆I177L Does Not Exhibit Residual Virulence in Long-Term Clinical Studies

Pathogens, 2023
African swine fever (ASF) is an important disease in swine currently producing a pandemic affecting pig production worldwide. Except in Vietnam, where two vaccines were recently approved for controlled use in the field, no vaccine is commercially ...
M. Borca, E. Ramirez-Medina, Ediane Silva, A. Rai, N. Espinoza, L. Velázquez-Salinas, D. Gladue   +6 more
semanticscholar   +1 more source

Seroimmunotyping of ASFV strains.

, 2022
Seroimmunotyping of ASFV strains.
Alexey D. Sereda (12536612), Anna S. Kazakova (12536615), Denis V. Kolbasov (12536621), Sanzhi G. Namsrayn (13014909), Mikhail E. Vlasov (13014912)   +4 more
core   +1 more source

A Cell-Adapted Live-Attenuated Vaccine Candidate Protects Pigs against the Homologous Strain VNUA-ASFV-05L1, a Representative Strain of the Contemporary Pandemic African Swine Fever Virus

Viruses, 2023
African swine fever (ASF) is a lethal and highly contagious transboundary animal disease with the potential for rapid international spread. Currently, there is no ASF vaccine commercially available.
Quang Lam Truong, Li-Hua Wang, Tuan Anh Nguyen, H. T. Nguyen, S. D. Tran, Anh Thi Vu, Anh Dao Le, V. Nguyen, P. Hoang, Yen Thi Hoang Nguyen, T. Le, Thang Nguyen Van, Thi My Le Huynh, H. L. T. Lai, R. Madera, Yu-Zhen Li, Ji-Shu Shi, L. T. Nguyen   +17 more
semanticscholar   +1 more source

The 24.5-kb Left Variable Region Is Not a Determinant for African Swine Fever Virus to Replicate in Primary Porcine Alveolar Macrophages

Viruses, 2022
African swine fever (ASF) is a widespread hemorrhagic and highly contagious infectious disease caused by African swine fever virus (ASFV), currently threatening the pig industry worldwide. Here, we demonstrated that the cell-adapted strain ASFV-P121 with
Rui Luo, Tao Wang, Maowen Sun, Li Pan, Shujian Huang, Yun Sun, Hua-Ji Qiu   +6 more
doaj   +1 more source