Results 41 to 50 of about 7,847 (206)

A blocking ELISA based on virus-like nanoparticles chimerized with an antigenic epitope of ASFV P54 for detecting ASFV antibodies

Scientific Reports, 2023
AbstractAfrican swine fever virus (ASFV) is a highly lethal pathogen of domestic and wild pigs. Due to no vaccines or drugs available, early accurate diagnosis and eradication of infected animals are the most important measures for ASFV prevention and control.
Chaohua Huang, Chenfu Cao, Zhichao Xu, Yanxing Lin, Jiang Wu, Qiaoyu Weng, Zheng Liu, Ye Jin, Peng Chen, Qunyi Hua   +9 more
openaire   +3 more sources

The attenuated ASFV strains MK-200 and FK-32/135 as possible models for investigation of protective immunity by ASFV infection

PLOS ONE, 2022
African swine fever (ASF) is an infectious disease of domestic and wild pigs of all breeds and ages, with the acute form of the disease being characterized by high fever, hemorrhages in the reticuloendothelial system and a high mortality rate. Registered safe and efficacious ASF vaccines are not available.
Alexey D. Sereda, Anna S. Kazakova, Sanzhi G. Namsrayn, Mikhail E. Vlasov, Denis V. Kolbasov   +4 more
openaire   +3 more sources

The 24.5-kb Left Variable Region Is Not a Determinant for African Swine Fever Virus to Replicate in Primary Porcine Alveolar Macrophages

Viruses, 2022
African swine fever (ASF) is a widespread hemorrhagic and highly contagious infectious disease caused by African swine fever virus (ASFV), currently threatening the pig industry worldwide. Here, we demonstrated that the cell-adapted strain ASFV-P121 with
Rui Luo, Tao Wang, Maowen Sun, Li Pan, Shujian Huang, Yun Sun, Hua-Ji Qiu   +6 more
doaj   +1 more source

Estimating the basic reproductive number (R0) for African Swine Fever Virus (ASFV) transmission between pig herds in Uganda [PDF]

, 2015
African swine fever (ASF) is a highly contagious, lethal and economically devastating haemorrhagic disease of domestic pigs. Insights into the dynamics and scale of virus transmission can be obtained from estimates of the basic reproduction number (R0 ...
Bett, Bernard, Eric M. Fèvre (125784), Fevre, Eric M., Barongo, MB, Charles Masembe, Okoth, Edward A., Bett, B, Stahl, K., Okoth, Edward, Richard P Bishop, Ståhl, K, Richard P. Bishop (222501), Barongo, M.B., Aliro, T., Mike B Barongo, Bishop, RP, Stahl, Karl, Karl Ståhl (399507), Bernard Bett (734348), Bett, Bernard K., Charles Masembe (726900), Barongo, Mike B., Ssematimba, Amos, Darryn Knobel, Bishop, Richard P., Karl Ståhl, Edward Okoth, Ssematimba, A., Masembe, Charles, Mike B. Barongo (734347), Amos Ssematimba (151239), Aliro, Tony, Bernard Bett, Knobel, D, Eric M Fèvre, Masembe, C, Fèvre, EM, Ssematimba, A, Masembe, C., Amos Ssematimba, Edward Okoth (734350), Aliro, T, Knobel, D.L., Tony Aliro (734349), Darryn Knobel (252700), Knobel, Darryn Leslie, Tony Aliro, Okoth, E   +47 more
core   +1 more source

MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway

mBio, 2022
African swine fever (ASF)—an aggressive infectious disease caused by the African swine fever virus (ASFV)—is significantly unfavorable for swine production. ASFV has a complex structure and encodes 150–167 proteins; however, the function of most of these
Keshan Zhang, Bo Yang, Chaochao Shen, Ting Zhang, Yu Hao, Dajun Zhang, Huanan Liu, Xijuan Shi, Guoli Li, Jinke Yang, Dan Li, Zixiang Zhu, Hong Tian, Fan Yang, Yi Ru, Wei Jun Cao, Jianhong Guo, Jijun He, Haixue Zheng, Xiangtao Liu   +19 more
doaj   +1 more source

Brequinar inhibits African swine fever virus replication in vitro by activating ferroptosis

Virology Journal, 2023
Background African swine fever virus (ASFV) is one of the most fatal swine etiological agents and has a huge economic impact on the global pork industry. Given that no effective vaccines or anti-ASFV drugs are available, there remains a pressing need for
Yang Chen, Yanchen Guo, Hao Chang, Zebu Song, Zhi Wei, Zhao Huang, Zezhong Zheng, Guihong Zhang, Yankuo Sun   +8 more
doaj   +1 more source

Cellular immunity in ASFV responses

Virus Research, 2013
African swine fever virus (ASFV) infection usually results in an acute haemorrhagic disease with a mortality rate approaching 100% in domestic pigs. However, pigs can survive infection with less-virulent isolates of ASFV and may become chronically infected.
Haru-Hisa, Takamatsu, Michael S, Denyer, Anna, Lacasta, Catrina M A, Stirling, Jordi M, Argilaguet, Christopher L, Netherton, Chris A L, Oura, Carlos, Martins, Fernando, Rodríguez   +8 more
openaire   +2 more sources

The MGF360-16R ORF of African Swine Fever Virus Strain Georgia Encodes for a Nonessential Gene That Interacts with Host Proteins SERTAD3 and SDCBP

Viruses, 2020
African swine fever virus (ASFV) causes a contagious and frequently lethal disease of pigs with significant economic consequences to the swine industry.
Elizabeth Ramírez-Medina, Elizabeth A. Vuono, Lauro Velazquez-Salinas, Ediane Silva, Ayushi Rai, Sarah Pruitt, Keith A. Berggren, James Zhu, Manuel V. Borca, Douglas P. Gladue   +9 more
doaj   +1 more source

Evaluation of the Function of ASFV Gene E66L in the Process of Virus Replication and Virulence in Swine

Viruses, 2023
African swine fever virus (ASFV) is the etiological agent of an economically important disease of swine currently affecting large areas of Africa, Eurasia and the Caribbean.
Elizabeth Ramirez-Medina, Elizabeth A. Vuono, Ayushi Rai, Nallely Espinoza, Alyssa Valladares, Edward Spinard, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +8 more
doaj   +1 more source

ASFV occurence data (Dellicour et al., 2020)

, 2021
Link to the Zenodo Repository containing ASFV occurence data in Wallonia (Belgium): https://doi.org/10.5281/zenodo.3764823 (Dellicour et al., 2020).Note: The ASFV occurence data can be accessed through Data_130919 ...
Martijn Bollen (10910385)
core   +1 more source