Results 51 to 60 of about 7,847 (206)

Marine fungal metabolites as antiviral agents: Computer-aided drug screening for selective inhibition of African swine fever virus dUTPase [PDF]

open access: yesBioImpacts
Introduction: African swine fever (ASF) continues to be a significant threat to the global livestock industry due to its severe impact on pig populations. Currently, there are no approved therapeutic agents for the virus, and biosecurity measures such as
Mark Andrian B. Macalalad   +1 more
doaj   +1 more source

X69R Is a Non-Essential Gene That, When Deleted from African Swine Fever, Does Not Affect Virulence in Swine

open access: yesViruses, 2020
African swine fever virus (ASFV) is currently causing devastating outbreaks in Asia and Europe, and the ASFV strain Georgia (ASFV-G) is responsible for these outbreaks.
Elizabeth Ramirez-Medina   +8 more
doaj   +1 more source

Noblis ASFV PCR Assays

open access: yes, 2022
Predicted PCR assays for detection of ASFV, including genotypes I and II deverloped at Nobils, Inc. using the BioLaboro pipeline, which includes BioVelocity, Primer 3, and PSET.
Katharine Jennings (12818321)   +4 more
core   +1 more source

Insights into the function of ESCRT complex and LBPA in ASFV infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The African swine fever virus (ASFV) is strongly dependent on an intact endocytic pathway and a certain cellular membrane remodeling for infection, possibly regulated by the endosomal sorting complexes required for transport (ESCRT). The ESCRT machinery is mainly involved in the coordination of membrane dynamics; hence, several viruses exploit this ...
Barrado-Gil, Lucía   +4 more
openaire   +4 more sources

Evaluation in Swine of a Recombinant Georgia 2010 African Swine Fever Virus Lacking the I8L Gene

open access: yesViruses, 2020
African swine fever virus (ASFV) is the causative agent of African swine fever, a disease currently causing significant economic losses in Europe and Asia. Specifically, the highly virulent ASFV strain Georgia 2010 (ASFV-G) is producing disease outbreaks
Elizabeth Vuono   +9 more
doaj   +1 more source

The African swine fever isolate ASFV-Kenya-IX-1033 is highly virulent and stable after propagation in the wild boar cell line WSL [PDF]

open access: yes, 2022
We describe the characterization of an African swine fever genotype IX virus (ASFV-Kenya-IX-1033), which was isolated from a domestic pig in western Kenya during a reported outbreak. This includes the efficiency of virus replication and in vivo virulence,
Johanneke D. Hemmink   +23 more
core   +1 more source

Modelling and stability analysis of ASFV with swill and the virus in the environment

open access: yesMathematical Biosciences and Engineering, 2022
<abstract><p>African swine fever (ASF) is an acute, hemorrhagic and severe infectious disease caused by the African swine fever virus (ASFV), and leads to a serious threat to the pig industry in China. Yet the impact of the virus in the environment and contaminated swill on the ASFV transmission is unclear in China.
Haitao Song   +3 more
openaire   +3 more sources

ASFV infection and replication in NPC1 KO cells.

open access: yes, 2022
Percentage of B54GFP infected cells (1 pfu/ml) at 16hpi in WT, Empty and NPC1 KO Vero cells detected by flow cytometry. Percentages were normalized to values in WT cells.
Fátima Lasala (394781)   +11 more
core   +1 more source

Artificial Insemination as an Alternative Transmission Route for African Swine Fever Virus

open access: yesPathogens, 2022
The rapid spread of the African swine fever virus (ASFV), causing severe disease with often high fatality rates in Eurasian suids, prevails as a threat for pig populations and dependent industries worldwide.
Virginia Friedrichs   +12 more
doaj   +1 more source

AT-rich regions of the ASFV genome induce IFN-β.

open access: yes, 2022
(A) Comparison of the total AT-content of the ASFV genome with genomes of HSV-1, EBV and VZV. (B) The content and distribution of AT-rich regions in the genomes of ASFV were compared with those in the genomes of HSV-1 and VZV using the EMBOSS Isochore ...
Hai-Xue Zheng (544167)   +10 more
core   +1 more source

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