Results 51 to 60 of about 9,741 (217)

Establishment and Evaluation of a Multicolor Latex Microsphere-Based Lateral Flow Immunoassay for the Simultaneous Detection of Antibodies Against African and Classical Swine Fever Viruses. [PDF]

Transbound Emerg Dis
African swine fever (ASF), a highly fatal disease often termed the “number one killer” of pigs, presents clinical symptoms indistinguishable from classical swine fever (CSF), such as fever, diarrhea, and vomiting, complicating on‐site differential diagnosis.
Chen J, Shi Z, Ru Y, Luo J, Yang Q, Xie Y, Wang L, Zhou J, Zhang X, Wei J, Zhu Y, Tian H, Zheng H, Chen NH.   +13 more
europepmc   +2 more sources

Two African swine fever virus proteins derived from a common precursor exhibit different nucleocytoplasmic transport activities [PDF]

, 2004
African swine fever virus (ASFV), a large icosahedral deoxyvirus, is the causative agent of an economically relevant hemorrhagic disease that affects domestic pigs.
Eulálio, A., Nunes-Correia, I., Carvalho, A. L., Faro, C., Citovsky, V., Simões, S., Lima, M. C. Pedroso de   +6 more
core   +1 more source

Deletion of CD2-Like (CD2v) and C-Type Lectin-Like (EP153R) Genes from African Swine Fever Virus Georgia-∆9GL Abrogates Its Effectiveness as an Experimental Vaccine

Viruses, 2020
African swine fever virus (ASFV) is currently the most dreaded infectious disease affecting the global swine production industry. There is no commercial vaccine available, making the culling of infected animals the current solution to control outbreaks ...
Douglas P. Gladue, Vivian O’Donnell, Elizabeth Ramirez-Medina, Ayushi Rai, Sarah Pruitt, Elizabeth A. Vuono, Ediane Silva, Lauro Velazquez-Salinas, Manuel V. Borca   +8 more
doaj   +1 more source

Screening and identification of the dominant antigens of the African swine fever virus

Frontiers in Veterinary Science, 2023
African swine fever is a highly lethal contagious disease of pigs for which there is no vaccine. Its causative agent African swine fever virus (ASFV) is a highly complex enveloped DNA virus encoding more than 150 open reading frames.
Zhaoyang Xu, Zhaoyang Xu, Yifan Hu, Junbo Li, Junbo Li, Ancheng Wang, Xin Meng, Xin Meng, Lingchao Chen, Jianchao Wei, Wu Tong, Ning Kong, Lingxue Yu, Hai Yu, Tongling Shan, Guangzhi Tong, Guihua Wang, Hao Zheng, Hao Zheng   +18 more
doaj   +1 more source

Computational insights in CD58 binding to ASFV CD2v and in silico optimization of nanobody designs against the interface

Open Veterinary Journal
Background: African swine fever (ASF) continues to hamper pork production worldwide. In addition to vaccines, there is a need to develop curative therapeutics, such as highly-specific antibodies or nanobodies, against immunogenic proteins with important
Albert Neil Gura Dulay, Richelle Mae Evasco Padilla, Nyzar Mabeth Obenio Odchimar, Fredmoore Legaspi Orosco   +3 more
doaj   +1 more source

Lyophilization of ASFV vaccine candidate ASFV-G-ΔI177L offers long term stability

Scientific Reports
AbstractFor over a century African swine fever (ASF) has been causing outbreaks leading to devastating losses for the swine industry. The current pandemic of ASF has shown no signs of stopping and continues to spread causing outbreaks in additional countries.
Nallely Espinoza, Edward Spinard, Ayushi Rai, Elizabeth Ramirez-Medina, Alyssa Valladares, Amanda Meyers, Manuel V. Borca, Douglas P. Gladue   +7 more
openaire   +3 more sources

Deletion of the EP296R Gene from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs

Viruses, 2022
African swine fever virus (ASFV) causes a lethal disease (ASF) in domestic pigs, African swine fever (ASF). ASF is currently producing a pandemic affecting pig production across Eurasia, leading to a shortage of food accessibility.
Elizabeth A. Vuono, Elizabeth Ramirez-Medina, Sarah Pruitt, Ayushi Rai, Nallely Espinoza, Edward Spinard, Alyssa Valladares, Ediane Silva, Lauro Velazquez-Salinas, Manuel V. Borca, Douglas P. Gladue   +10 more
doaj   +1 more source

Evaluation of the risk factors contributing to the African swine fever occurrence in Sardinia, Italy [PDF]

, 2015
This study assesses the relation between hypothesized risk factors and African swine fever virus (ASFV) distribution in Sardinia (Italy) after the beginning of the eradication program in 1993, using a Bayesian multivariable logistic regression mixed ...
Feliziani, Francesco, Martínez López, Beatriz, Mur, Lina, Perez, Andres M, Rolesu, Sandro, Sánchez-Vizcaíno, José Manuel   +5 more
core   +4 more sources

African Swine Fever Virus (ASFV) Indirect ELISA Test Based on the Use of the Soluble Cytoplasmic Semi- purified Antigen (ASFV CP-Ag)

, 2022
The present chapter describes a simple and economic indirect enzyme immunoassay (ELISA ) for African swine fever virus (ASFV) antibody detection based on the use of the soluble cytoplasmic fraction of ASFV-infected monkey stable cells (MS). The soluble antigen proteins of ASFV-infected cells are separated by sucrose precipitation centrifugation, and ...
Carmina, Gallardo, Nieto, R, Arias, M
openaire   +3 more sources

Infection Characteristics and Transcriptomics of African Swine Fever Virus in Bama Minipigs

Microbiology Spectrum, 2022
Animal experiments on African swine fever virus (ASFV) are vital to the study of ASFV; however, ASFV can only infect pigs, and animal experiments need to be performed in animal biosafety level 3 (ABSL-3) laboratories, meaning that many small ABSL-3 ...
Changjie Lv, Jingyu Yang, Li Zhao, Chao Wu, Chao Kang, Qiang Zhang, Xiaomei Sun, Xi Chen, Zhong Zou, Meilin Jin   +9 more
doaj   +1 more source