Results 51 to 60 of about 11,516 (233)
mBio, 2022 African swine fever (ASF)—an aggressive infectious disease caused by the African swine fever virus (ASFV)—is significantly unfavorable for swine production. ASFV has a complex structure and encodes 150–167 proteins; however, the function of most of these
Keshan Zhang +19 more
doaj +1 more source
Viruses, 2023 African swine fever (ASF) causes high morbidity and mortality of both domestic pigs and wild boars and severely impacts the swine industry worldwide.
Liang-Zheng Yu +4 more
semanticscholar +1 more source
PLOS ONE, 2022 African swine fever (ASF) is an infectious disease of domestic and wild pigs of all breeds and ages, with the acute form of the disease being characterized by high fever, hemorrhages in the reticuloendothelial system and a high mortality rate. Registered safe and efficacious ASF vaccines are not available.
Alexey D. Sereda +4 more
openaire +3 more sources
Brequinar inhibits African swine fever virus replication in vitro by activating ferroptosis
Virology Journal, 2023 Background African swine fever virus (ASFV) is one of the most fatal swine etiological agents and has a huge economic impact on the global pork industry. Given that no effective vaccines or anti-ASFV drugs are available, there remains a pressing need for
Yang Chen +8 more
doaj +1 more source
AT-rich regions of the ASFV genome induce IFN-β.
, 2022 (A) Comparison of the total AT-content of the ASFV genome with genomes of HSV-1, EBV and VZV. (B) The content and distribution of AT-rich regions in the genomes of ASFV were compared with those in the genomes of HSV-1 and VZV using the EMBOSS Isochore ...
Hai-Xue Zheng (544167) +10 more
core +1 more source
Cellular immunity in ASFV responses
Virus Research, 2013 African swine fever virus (ASFV) infection usually results in an acute haemorrhagic disease with a mortality rate approaching 100% in domestic pigs. However, pigs can survive infection with less-virulent isolates of ASFV and may become chronically infected.
Haru-Hisa, Takamatsu +8 more
openaire +2 more sources
Polish journal of veterinary sciences, 2023 African swine fever virus (ASFV) causes feverous and hemorrhagic disease of domestic pigs and European wild boars with high mortality, yet no commercial vaccine is currently available.
Q. Chen +7 more
semanticscholar +1 more source
Viruses, 2020 African swine fever virus (ASFV) causes a contagious and frequently lethal disease of pigs with significant economic consequences to the swine industry.
Elizabeth Ramírez-Medina +9 more
doaj +1 more source
Marine fungal metabolites as antiviral agents: Computer-aided drug screening for selective inhibition of African swine fever virus dUTPase [PDF]
BioImpactsIntroduction: African swine fever (ASF) continues to be a significant threat to the global livestock industry due to its severe impact on pig populations. Currently, there are no approved therapeutic agents for the virus, and biosecurity measures such as
Mark Andrian B. Macalalad +1 more
doaj +1 more source
AT-rich regions of the ASFV genome activate RNA Pol-III-RIG-I axis.
, 2022 (A) RNAs extracted from poly(dA:dT)-, ASFV-AT-, ASFV-GC (1 μg/ml) or mock-transfected PK-15 cells (2×106) were treated with RNase A or DNase I at 37°C for 1 hour.
Hai-Xue Zheng (544167) +10 more
core +1 more source