Results 71 to 80 of about 7,847 (206)
Journal of Pure and Applied MicrobiologyAfrican swine fever (ASF), a deadly disease caused by African swine fever virus (ASFV), emerged in north-eastern India in 2020 and subsequently spread to several states, devastating swine herds due to the lack of commercial vaccines.
Gopal Sarkar +10 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral activity against multiple RNA ...
Rui Luo +9 more
wiley +1 more source
African Swine Fever Virus (ASFV): Immunity and Vaccine Development
Vaccines, 2023 African swine fever virus (ASFV) is the causative agent of the highly contagious disease African swine fever (ASF), which can result in mortality rates of up to 100% in pigs infected by virulent strains [...]
Kiramage Chathuranga, Jong-Soo Lee
openaire +3 more sources
Investigating the Heat Stability and Inactivation Conditions of Decapod Iridescent Virus 1 (DIV1)
Animal Research and One Health, EarlyView.Heat treatment effectively inactivates decapod iridescent virus 1 (DIV1) under milder conditions than current WOAH recommendations. DIV1 infectivity was eliminated at 56°C for 30 min, 60°C for 15 min, or 70°C for 1 min, providing optimized heat treatment strategies for aquaculture biosecurity and seafood safety.
Yonghui Feng +4 more
wiley +1 more source
Assessing Environment Resistance of the Korean Wild Boar ASFV Isolates “ ASFV/Yeoncheon/2019 ”
Transboundary and Emerging DiseasesAfrican swine fever (ASF) is a disease characterized by high mortality and severe hemorrhagic damage in swine breeds, leading to significant economic losses for domestic pig farm operations. Although the introduction route of ASF in South Korea remains unclear, the primary transmission is believed to be through contamination of ...
Hyunji Gu +14 more
openaire +2 more sources
Journal of Veterinary ResearchAfrican swine fever (ASF) is a devastating viral disease of domestic pigs and wild boar. As no safe vaccine is currently available, prevention relies primarily on strict biosecurity measures. Early diagnosis is essential to reduce the risk of ASF spread.
Walczak Marek, Adaszek Łukasz
doaj +1 more source
Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects
Interdisciplinary Medicine, EarlyView.Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou +6 more
wiley +1 more source
NPC2 downregulation reduced ASFV infectivity.
, 2022 (A) NPC1, NPC2 and tubulin (loading control) were detected by western blot in Vero cells transduced with SCR (scramble) and shNPC2 (34 and 36) lentiviral particles.
Fátima Lasala (394781) +11 more
core +1 more source
Lyophilization of ASFV vaccine candidate ASFV-G-ΔI177L offers long term stability
Scientific ReportsAbstractFor over a century African swine fever (ASF) has been causing outbreaks leading to devastating losses for the swine industry. The current pandemic of ASF has shown no signs of stopping and continues to spread causing outbreaks in additional countries.
Nallely Espinoza +7 more
openaire +3 more sources
Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics
Interdisciplinary Medicine, EarlyView.This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li +7 more
wiley +1 more source