Results 91 to 100 of about 5,108 (173)

Characterization of Potential Risk Pathways for African Swine Fever Introduction Into Brazil

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF) poses a serious threat to global swine production, and its reintroduction into Brazil, the world’s third‐largest pork exporter, would have severe socioeconomic consequences. This study characterized the potential risk pathways for ASF introduction in Brazil by analyzing three key aspects: seizure of informally imported animal ...
Isadora Martins Pinto Coelho, Érica Lorenza Martins Araújo, Breno Oliveira Lima Ramos, Ailton Junior Antunes da Costa, Lorena Diniz Macedo Silva Maia, Ana Luisa Martins Brum, João Paulo Amaral Haddad, Rafael Romero Nicolino, Fedor Korennoy   +8 more
wiley   +1 more source

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source

The deletion of the EP402R and MGF505/360 genes attenuates a genotype I/II recombinant ASFV but fails to confer complete protection against homologous or genotype II challenge in pigs

Emerging Microbes and Infections
African swine fever (ASF), a pig disease caused by ASFV, is highly contagious and often lethal. The recent emergence of novel ASFV with I/II genomic recombination has posed significant challenges to global ASF prevention and control.
Yao Li, Yingnan Liu, Zhuyun Sun, Zhenhua Xie, Chuanwen Tian, Rongrong Wang, Jun Gao, Maomao Wang, Jingyi Liu, Heng Wang, Guihong Zhang, Jie Li, Dongdong Di, Lang Gong, Hongjun Chen   +14 more
doaj   +1 more source

The C962R ORF of African Swine Fever Strain Georgia Is Non-Essential and Not Required for Virulence in Swine

Viruses, 2020
African swine fever virus (ASFV) is the causative agent of the African swine fever (ASF) epizootic currently affecting pigs throughout Eurasia, causing significant economic losses in the swine industry.
Elizabeth. Ramirez-Medina, Elizabeth. A. Vuono, Ayushi. Rai, Sarah. Pruitt, Ediane. Silva, Lauro. Velazquez-Salinas, James. Zhu, Manuel. V. Borca, Douglas. P. Gladue   +8 more
doaj   +1 more source

Emerging Challenges and Advances in Porcine Circovirus: A Decade in Review

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Over the past decade, porcine circoviruses (PCVs) have continued to pose a significant threat to global swine health, and pivotal discoveries have significantly reshaped our understanding of their biology and control. Extensive genomic surveillance has expanded porcine circovirus 2 (PCV2) genotyping from four to at least eight lineages, with PCV2d now ...
Jiawei Zheng, Guoqing Zhang, Peiheng Li, Linzhu Ren, Nan-hua Chen   +4 more
wiley   +1 more source

ASFV infection induces macrophage necroptosis and releases proinflammatory cytokine by ZBP1-RIPK3-MLKL necrosome activation

Frontiers in Microbiology
African swine fever (ASF) is an infectious disease characterized by hemorrhagic fever, which is highly pathogenic and causes severe mortality in domestic pigs. It is caused by the African swine fever virus (ASFV).
Dajun Zhang, Yu Hao, Xing Yang, Xijuan Shi, Dengshuai Zhao, Lingling Chen, Huanan Liu, Zixiang Zhu, Haixue Zheng   +8 more
doaj   +1 more source

Isolation and Pathogenicity of a Getah Virus With a Novel Deletion in the 3′ UTR

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The spread of Getah virus (GETV) in China has become increasingly severe due to long‐term neglect and the lack of vaccines, posing a threat to animal safety and public health. In this study, we isolated and identified a novel GETV strain, designated GETV‐CX7.
Yawei Sun, Haiyan Li, Wenxu Wang, Yaqing Shi, Dongzhuo Yang, Yingshuo Zhang, Jimei Du, Yongtao Li, Linyang Yu, Xianfeng Zhang, Lu Chen, Zu Zhang Wei   +11 more
wiley   +1 more source

ASFV epitope mapping by high density peptides microarrays

Virus Research
African swine fever (ASF) is an acute, highly contagious and deadly infectious disease. It is a threat to animal health with major potential economic and societal impact. Despite decades of ASF vaccine research, still some gaps in knowledge are hindering the development of a functional vaccine.
Cloé Desmet, Bruna Coelho-Cruz, Dora Mehn, Pascal Colpo, Ana Ruiz-Moreno   +4 more
openaire   +3 more sources

Identification of cepharanthine as an effective inhibitor of African swine fever virus replication

Emerging Microbes and Infections
African swine fever virus (ASFV) causes highly contagious swine disease, African swine fever (ASF), thereby posing a severe socioeconomic threat to the global pig industry and underscoring that effective antiviral therapies are urgently required.
Chuanxiang Qi, Jiyoung Lee, Yongqiang Zhang, Huan Chen, Jiaxuan Lv, Zhenzhong Wang, Jinming Li, Xiaodong Wu, Yong-Sam Jung, Zhiliang Wang, Yingjuan Qian   +10 more
doaj   +1 more source

When ASFV Infection Meets the cGAS‐STING Signaling Pathway

Transboundary and Emerging Diseases
The African swine fever virus (ASFV) has the ability to infect both wild boars and domestic pigs, regardless of their breeds or ages, often resulting in a mortality rate of 100%. Host innate immunity is the most important defense weapon against invasion of pathogenic microbial infection.
Songbiao Chen, Ke Shang, Ying Wei, Jian Chen, Zuhua Yu, Lei He, Ke Ding   +6 more
openaire   +2 more sources