Results 111 to 120 of about 7,847 (206)
ASFV epitope mapping by high density peptides microarrays
Virus ResearchAfrican swine fever (ASF) is an acute, highly contagious and deadly infectious disease. It is a threat to animal health with major potential economic and societal impact. Despite decades of ASF vaccine research, still some gaps in knowledge are hindering the development of a functional vaccine.
Cloé Desmet +4 more
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African Swine Fever Virus (ASFV), resulting in strain-dependent vascular pathology, leading to hemorrhagic fever, is an important pathogen in swine. The pathogenesis of ASFV is determined by the array and spatial distribution of susceptible cells within ...
N. Balmelle +7 more
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pCMV-UbsHAPQ protects against lethal ASFV challenge.
, 2013 (A) PBMCs from pigs immunized twice (2x) or 4 times (4x) with pCMV-UbsHAPQ or with pCMV, were in vitro stimulated with media (negative control), with the E75 ASFV isolate (105 HAU50/ml), with a mix of the p54, p30 and HA ASFV proteins (6 μg/ml of each ...
Ivan Galindo-Cardiel (305465) +12 more
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ASFV antagonizes RNA Pol-III-RIG-I axis.
, 2022 (A) ASFV infection inhibits poly(dA:dT)-induced transcription of IFNB1, IL6 and TNFA. PAMs (2×106) were uninfected or infected with ASFV (MOI = 0.1) for the indicated times, and then were stimulated with transfected poly(dA:dT) (1 μg/ml) for 4 hours ...
Hai-Xue Zheng (544167) +10 more
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ASFV infection induces lipid metabolic disturbances and promotes viral replication
IntroductionAfrican swine fever is a highly transmissible and lethal infectious disease caused by the African swine fever virus (ASFV), which has considerably impacted the global swine industry. Lipid metabolism plays a vital role in sustaining lipid and
Ruihong Li +12 more
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Background/Objectives: African Swine Fever (ASF) represents one of the most serious threats to animal health and global food security. The causative agent of ASF is the African swine fever virus (ASFV), a DNA virus belonging to the Asfarviridae family.
Francesco Manfredi +11 more
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A triple protein-based ELISA for differential detection of ASFV antibodies
Frontiers in Veterinary ScienceAfrican swine fever (ASF) caused by the ASF virus (ASFV) is a severe and highly contagious viral disease that poses a significant threat to the global pig industry. As no vaccines or effective drugs are available to aid prevention and control, early detection is crucial. The emergence of the low-virulence ASFV strain not expressing CD2v/MGFs (ASFVΔCD2v/
Shuai Zhang +6 more
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When ASFV Infection Meets the cGAS‐STING Signaling Pathway
Transboundary and Emerging DiseasesThe African swine fever virus (ASFV) has the ability to infect both wild boars and domestic pigs, regardless of their breeds or ages, often resulting in a mortality rate of 100%. Host innate immunity is the most important defense weapon against invasion of pathogenic microbial infection.
Songbiao Chen +6 more
openaire +2 more sources
ASFV disassembly in swine macrophages.
, 2016 Macrophages were infected with ASFV (MOI 100) for 10, 15, 30, 45, 60 and 90 min and processed by EM. A-D) Selected EM images of the endosomal transport and the disassembly process undergone by ASFV. After endocytosis, incoming extracellular particles (A)
Germán Andrés (2626936) +3 more
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Porcine macrophages: ASFV-infected vs. mock-infected
, 2019 Transcriptional profiling of porcine macrophages infected with Afraican swine fever virus (ASFV) infected cells and mock infection was conducted in this experiment. Overall design: Two-condition experiment: ASFV infected vs.
PIADC, Foreign Animal Disease Research Unit, USDA-ARS (17856188)
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