Results 131 to 140 of about 11,516 (233)

Digital Point‐of‐Care Testing Device Based on Bioluminescent Pyrophosphate in Real‐Time and Recombinase‐aid Amplification

Advanced Intelligent Systems, Volume 8, Issue 3, March 2026.
A point‐of‐care testing method based on solvent‐responsive magnetic beads suitable for large‐area diagnosis and mutation screening in remote areas was developed to detect it by combining bioluminescenct pyrophosphate in real‐time technology and recombinase‐aid amplification technology.
Zhongjie Fei, Juan Bai, Liwei Xu, Siyi Wang, Pengfeng Xiao, Dongrui Zhou, Guanxiong Liu, Rongbin Wei, Ping Jiang   +8 more
wiley   +1 more source

Whole genome sequencing of ASFV-intB318L.

African swine fever (ASF) is an acute, hemorrhagic, and severe infectious disease caused by the ASF virus (ASFV). ASFV has evolved multiple strategies to escape host antiviral immune responses.
Chunying Feng (12428466), Weiye Chen (3234612), Jiangnan Li (658317), Qiongqiong Zhou (92521), Zhaoxia Zhang (3714328), Xiaohong Liu (50816), Liang Hu (202392), Yuntao Guan (368332), Changjiang Weng (8127537), Guangqiang Ye (18369131), Xijun He (663738), Zhengshuang Wu (18369134), Xianfeng Zhang (295346), Dongming Zhao (296447), Li Huang (107408), Hongyang Liu (303058), Zhigao Bu (146375), Hefeng Chen (7834751)   +17 more
core   +1 more source

Safeguarding a Flagship Species: Integrated Surveillance of Cross‐Species Pathogen Transmission in Giant Panda Ecosystems

Ecology and Evolution, Volume 16, Issue 3, March 2026.
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun, Yi Peng, Xiaoye Hao, Rong Dong, Zhilin Wang, Le Wang, Chengdong Wang, Xiangdong Wu, Zheng Chen, Wenbo Zhang, Xiaoli Tang   +10 more
wiley   +1 more source

The deletion of the EP402R and MGF505/360 genes attenuates a genotype I/II recombinant ASFV but fails to confer complete protection against homologous or genotype II challenge in pigs

Emerging Microbes and Infections
African swine fever (ASF), a pig disease caused by ASFV, is highly contagious and often lethal. The recent emergence of novel ASFV with I/II genomic recombination has posed significant challenges to global ASF prevention and control.
Yao Li, Yingnan Liu, Zhuyun Sun, Zhenhua Xie, Chuanwen Tian, Rongrong Wang, Jun Gao, Maomao Wang, Jingyi Liu, Heng Wang, Guihong Zhang, Jie Li, Dongdong Di, Lang Gong, Hongjun Chen   +14 more
doaj   +1 more source

Identification and utility of innate immune system evasion mechanisms of ASFV

Virus Research, 2013
The interferon (IFN) system is an early innate anti-virus host defense mechanism that takes place shortly after entry of the pathogen and long before the onset of adaptive immunity. Thus, African swine fever virus (ASFV), as an acute and persistent virus in pigs, is predicted to have evolved multiple genes for the manipulation and evasion of interferon.
Sílvia, Correia, Sónia, Ventura, Robert Michael, Parkhouse   +2 more
openaire   +2 more sources

Duration of immunity following infection with moderately virulent ASFV

PLOS Pathogens
Abstract African swine fever virus (ASFV) poses a significant threat to pork production and wild pig populations worldwide. The study assessed the long-term fate and immunity of animals recovering from a moderately virulent ASFV infection, following the principles of a duration of immunity study for live vaccines ...
Virginia Friedrichs, Paul Deutschmann, Kerstin Wernike, Tessa Carrau, Martin Beer, Sandra Blome, Alexander Schäfer   +6 more
openaire   +3 more sources

ASFV epitope mapping by high density peptides microarrays

Virus Research
African swine fever (ASF) is an acute, highly contagious and deadly infectious disease. It is a threat to animal health with major potential economic and societal impact. Despite decades of ASF vaccine research, still some gaps in knowledge are hindering the development of a functional vaccine.
Cloé Desmet, Bruna Coelho-Cruz, Dora Mehn, Pascal Colpo, Ana Ruiz-Moreno   +4 more
openaire   +3 more sources

CD1D knockout swine are permissive to African swine fever virus genotype II infection

Emerging Microbes and Infections
African swine fever virus (ASFV) is an important pathogen of domestic and wild suids and the causative agent of African swine fever (ASF). ASFV displays a tropism for myeloid cells, predominately of the monocyte/macrophage lineage, which is critical for ...
Daniel Madden, Jessie D. Trujillo, Shanmugasundaram Elango, Isaac Fitz, Chester D. McDowell, Patricia Assato, Eulim Lyoo, Taeyong Kwon, Konner Cool, Yonghai Li, Franco Matias Ferreyra, Natasha N. Gaudreault, Igor Morozov, Kiho Lee, John Driver, Juergen A. Richt   +15 more
doaj   +1 more source

High-throughput and all-solution phase African Swine Fever Virus (ASFV) detection using CRISPR-Cas12a and fluorescence based point-of-care system

bioRxiv, 2019
Here we report the development of a high throughput, all-solution phase, and isothermal detection system to detect African Swine Fever Virus (ASFV). CRISPR-Cas12a programmed with a CRISPR RNA (crRNA) is used to detect ASFV target DNA.
Qian He, Dong-Mei Yu, Mengdi Bao, Grant Korensky, Ju-Hong Chen, Mingyeong Shin, Juwon Kim, Myeongkee Park, Pei-Wu Qin, Ke Du   +9 more
semanticscholar   +1 more source

Porcine macrophages: ASFV-infected vs. mock-infected

, 2019
Transcriptional profiling of porcine macrophages infected with Afraican swine fever virus (ASFV) infected cells and mock infection was conducted in this experiment. Overall design: Two-condition experiment: ASFV infected vs.
PIADC, Foreign Animal Disease Research Unit, USDA-ARS (17856188)
core