Results 101 to 110 of about 11,516 (233)

Function investigation of p11.5 in ASFV infection

Virologica Sinica
Virus replication relies on complex interactions between viral proteins. In the case of African swine fever virus (ASFV), only a few such interactions have been identified so far. In this study, we demonstrate that ASFV protein p72 interacts with p11.5 using co-immunoprecipitation and liquid chromatography-mass spectrometry (LC-MS).
Dan Yin, Bin Shi, Renhao Geng, Yingnan Liu, Lang Gong, Hongxia Shao, Kun Qian, Hongjun Chen, Aijian Qin   +8 more
openaire   +2 more sources

Immune cell early activation, apoptotic kinetic, and T-cell functional impairment in domestic pigs after ASFV CADC_HN09 strain infection

Frontiers in Microbiology
African swine fever (ASF) caused by the African swine fever virus (ASFV) is a fatal and highly contagious disease of domestic pigs characterized by rapid disease progression and death within 2 weeks.
Yunfei Tian, Dongyue Wang, Shicheng He, Zhen Cao, Wencai Li, Fei Jiang, Yi-Fan Shi, Yuxin Hao, Xinhao Wei, Qingqing Wang, Shuai Qie, Jiangtao Wang, Ting Li, Xiao-Li Hao, Jian-Zhong Zhu, Jiajun Wu, S. Shang, Xinyan Zhai   +17 more
semanticscholar   +1 more source

Development of a ladder-shape melting temperature isothermal amplification (LMTIA) assay for detection of African swine fever virus (ASFV)

Journal of Veterinary Sciences, 2022
Background Due to the unavailability of an effective vaccine or antiviral drug against the African swine fever virus (ASFV), rapid diagnosis methods are needed to prevent highly contagious African swine fever.
Yong-Zhen Wang, Bo-Rui Wang, Dan Xu, Meng Zhang, Xiaohua Zhang, De-Guo Wang   +5 more
semanticscholar   +1 more source

Unveiling Shared Immune Responses in Porcine Alveolar Macrophages during ASFV and PRRSV Infection Using Single-Cell RNA-seq

Microorganisms
African swine fever virus (ASFV) and porcine reproductive and respiratory syndrome virus (PRRSV) infections lead to severe respiratory diseases in pigs, resulting in significant economic losses for the global swine industry.
Bo Jiang, Lu Li, Yu Wu, Xiaoying Wang, Ning Gao, Zhichao Xu, Chunhe Guo, Sheng-Dong He, Gui-Hong Zhang, Yao-Sheng Chen, Xiao-Hong Liu, Zheng-Cao Li   +11 more
semanticscholar   +1 more source

Evaluation of Multi‐Stakeholder Perspectives on the Preparedness of Ghana's Animal Health Services for African Swine Fever Control: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims African Swine Fever (ASF) is a highly fatal viral disease of pigs that has persisted in Ghana since its first introduction in 1999, causing recurrent outbreaks with devastating socioeconomic consequences for livelihoods and food security.
Emmanuel Allege‐Cudjoe, Benjamin Obukowho Emikpe, Evans Nsoh Ayamdooh, Mabel Abudu, Helena Naa Baake Acquah, Abdul Rahman Yakubu, Sampson Yeboah, Prince Nana Takyi, Joseph Kofi Abuh, Patrick Amponsah Mensah, Emmanuel Eshun, Felix Doe, Patrick Ababio, Emmah Nafula Kwoba, Edmond Onidje, Ziekah Yiryele Meyir, William Tasiame, Joseph Atawalna, Garba Maina Ahmed, Marcel Ohoukou Boka, Abebe Wolde, Anthony Akunzule, Charles Mensah, Edward Danso Fenteng   +23 more
wiley   +1 more source

Evaluation of Cellular Immunity with ASFV Infection by Swine Leukocyte Antigen (SLA)—Peptide Tetramers

, 2021
African swine fever virus (ASFV) causes acute hemorrhagic fever in domestic pigs and wild boars, resulting in incalculable economic losses to the pig industry. As the mechanism of viral infection is not clear, protective antigens have not been discovered
Tingrong Luo, Jing Li, He Zhang, Wenhui Fan, Wenjun Liu, Lei Sun, Yu Qi, Teng Chen, Wenqiang Sun, Lihong He, Rongliang Hu, Xintao Zhou   +11 more
core   +1 more source

Evaluation of Cross-Protection of African Swine Fever Vaccine ASFV-G-ΔI177L Between ASFV Biotypes

Vaccines
Background/Objectives: Vaccine development for the prevention of ASF has been very challenging due to the extensive genetic and largely unknown antigenic diversity. Inactivated vaccines, using different inactivation methods and a variety of adjuvants, have been consistently inefficacious.
Manuel V. Borca, Elizabeth Ramirez-Medina, Christine Mutisya, Rose Ojuok, Josiah Odaba, Mark Dihbol, Anna Lacasta, Douglas P. Gladue   +7 more
openaire   +2 more sources

Deletion of the EP296R Gene from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs

Viruses, 2022
African swine fever virus (ASFV) causes a lethal disease (ASF) in domestic pigs, African swine fever (ASF). ASF is currently producing a pandemic affecting pig production across Eurasia, leading to a shortage of food accessibility.
Elizabeth A. Vuono, Elizabeth Ramirez-Medina, Sarah Pruitt, Ayushi Rai, Nallely Espinoza, Edward Spinard, Alyssa Valladares, Ediane Silva, Lauro Velazquez-Salinas, Manuel V. Borca, Douglas P. Gladue   +10 more
doaj   +1 more source

Deletion of the ASFV dUTPase Gene E165R from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs

Viruses, 2022
African swine fever (ASF) is a frequently lethal disease of domestic and wild swine currently producing a pandemic affecting pig production in Eurasia.
E. Vuono, E. Ramirez-Medina, S. Pruitt, A. Rai, N. Espinoza, Ediane Silva, L. Velázquez-Salinas, D. Gladue, M. Borca   +8 more
semanticscholar   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source