Results 81 to 90 of about 11,516 (233)

Growth Kinetics of African Swine Fever Virus (Genotype II) Isolated from a Domestic Pig in Punjab, India

Journal of Pure and Applied Microbiology
African swine fever (ASF), a deadly disease caused by African swine fever virus (ASFV), emerged in north-eastern India in 2020 and subsequently spread to several states, devastating swine herds due to the lack of commercial vaccines.
Gopal Sarkar, Katherukamem Rajukumar, Dhanapal Senthilkumar, Fateh Singh, Govindarajulu Venkatesh, Jaswant Patel, Rohit Sahu, Nourin Khan, Amandeep, Vijendra Pal Singh, Aniket Sanyal   +10 more
doaj   +1 more source

Development and Application of RAA Nucleic Acid Test Strip Assay and Double RAA Gel Electrophoresis Detection Methods for ASFV and CSFV

Frontiers in Molecular Biosciences, 2022
African swine fever (ASF) is an acute, severe and hemorrhagic infectious disease caused by African swine fever virus (ASFV) infecting domestic pigs and wild boars. Since the outbreak of the disease in China in 2018, it has brought a great impact on China’
Keke Wu, Yuanyuan Zhang, S. Zeng, Xiao-Di Liu, Yuwan Li, Xiaowen Li, Wen-Xian Chen, Zhao-Yao Li, Yu-Wei Qin, Jin-Ding Chen, Shuang-Qi Fan   +10 more
semanticscholar   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

ASFV epidemic model parameters.

, 2019
ASFV epidemic model parameters.
Adrian Self (8086847), Tanvir Ferdousi (8086841), Sifat Afroj Moon (8086844), Caterina Scoglio (319581)   +3 more
core   +1 more source

The problem of the universality of biological models for in vitro replication of virulent and attenuated strains of African swine fever virus (Asfarviridae: Asfivirus), classical swine fever virus (Flaviviridae: Pestivirus), and porcine reproductive and respiratory syndrome virus (Arteriviridae: Betaarterivirus)

Вопросы вирусологии
Introduction. The current state of pig industry in Russia is characterized by the dominance of pig farms of III–IV compartments and a reduction in livestock in private subsidiary and peasant farms against the background of the spread of infectious ...
Danila S. Moiseenko, Anastasia S. Sadchikova, Elena V. Chernyshova, Alexey S. Igolkin, Natalia I. Bakhtieva, Elena G. Kuznetsova, Nikolay A. Kolchanov, Elena A. Trofimova, Irina V. Vologina, Vera L. Gavrilova, Olga S. Puzankova, Roman S. Chernyshev   +11 more
doaj   +1 more source

Deletion of CD2-Like (CD2v) and C-Type Lectin-Like (EP153R) Genes from African Swine Fever Virus Georgia-∆9GL Abrogates Its Effectiveness as an Experimental Vaccine

Viruses, 2020
African swine fever virus (ASFV) is currently the most dreaded infectious disease affecting the global swine production industry. There is no commercial vaccine available, making the culling of infected animals the current solution to control outbreaks ...
Douglas P. Gladue, Vivian O’Donnell, Elizabeth Ramirez-Medina, Ayushi Rai, Sarah Pruitt, Elizabeth A. Vuono, Ediane Silva, Lauro Velazquez-Salinas, Manuel V. Borca   +8 more
doaj   +1 more source

Dihydromyricetin inhibits African swine fever virus replication by downregulating toll-like receptor 4-dependent pyroptosis in vitro

Veterinary Research, 2023
African swine fever (ASF), caused by ASF virus (ASFV) infection, poses a huge threat to the pork industry owing to ineffective preventive and control measures. Hence, there is an urgent need to develop strategies, including antiviral drugs targeting ASFV,
Yang Chen, Zebu Song, Hao Chang, Yanchen Guo, Zhi Wei, Yankuo Sun, Lang Gong, Zezhong Zheng, Guihong Zhang   +8 more
doaj   +1 more source

Infection of domestic pigs with a genotype II potent strain of ASFV causes cytokine storm and lymphocyte mass reduction

Frontiers in Immunology
The whole-genome sequence of an African swine fever virus (ASFV) strain (HuB/HH/2019) isolated from Hubei, China, was highly similar to that of the Georgia 2007/1 strain ASFV.
Xuezhi Zuo, Guorui Peng, Jun-Jie Zhao, Qi-Zu Zhao, Yuan-Yuan Zhu, Yuan Xu, Lu Xu, Fangtao Li, Ying-Ju Xia, Ye-Bing Liu, Cheng Wang, Zhen Wang, Hai-Dong Wang, Xing-Qi Zou   +13 more
semanticscholar   +1 more source

Deletion of the L7L-L11L Genes Attenuates ASFV and Induces Protection against Homologous Challenge

Viruses, 2021
African swine fever (ASF), caused by the African swine fever virus (ASFV), is a major epidemic disease endangering the swine industry. Although a number of vaccine candidates have been reported, none are commercially available yet.
Jing-Yuan Zhang, Yan-Yan Zhang, Teng Chen, Jinjin Yang, Huixian Yue, Lidong Wang, Xintao Zhou, Y. Qi, Xun Han, Junnan Ke, Shuchao Wang, Jin-Mei Yang, Fa-Ming Miao, Shou-Feng Zhang, Fei Zhang, Ying Wang, Min Li, Rong-Liang Hu   +17 more
semanticscholar   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, Volume 13, Issue 57, 14 October 2026.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source