Results 11 to 20 of about 5,108 (173)

ASFV Gene A151R Is Involved in the Process of Virulence in Domestic Swine

open access: yesViruses, 2022
African swine fever virus (ASFV) is the etiological agent of a swine pandemic affecting a large geographical area extending from Central Europe to Asia. The viral disease was also recently identified in the Dominican Republic and Haiti.
Elizabeth Vuono   +2 more
exaly   +5 more sources

Structures and Functional Diversities of ASFV Proteins [PDF]

open access: yesViruses, 2021
African swine fever virus (ASFV), the causative pathogen of the recent ASF epidemic, is a highly contagious double-stranded DNA virus. Its genome is in the range of 170~193 kbp and encodes 68 structural proteins and over 100 non-structural proteins. Its high pathogenicity strains cause nearly 100% mortality in swine.
Zhongzhou Chen, Chen Zhongzhou
exaly   +4 more sources

Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-ΔI177L

open access: yesViruses, 2022
African swine fever (ASF) is the cause of a recent pandemic that is posing a threat to much of the world swine production. The etiological agent, ASF virus (ASFV), infects domestic and wild swine, producing a variety of clinical presentations depending on the virus strain and the genetic background of the pigs infected.
Ayushi Rai   +2 more
exaly   +4 more sources

Interactome between ASFV and host immune pathway proteins

open access: yesmSystems, 2023
African swine fever virus (ASFV) causes severe acute hemorrhagic disease with high mortality in domestic pigs but minimal or no symptoms to warthogs, for which the underlying mechanism remains elusive.
Qijun Wu   +13 more
doaj   +3 more sources

Expression of a recombinant ASFV P30 protein and production of monoclonal antibodies

open access: yesOpen Veterinary Journal, 2023
Background: African Swine Fever (ASF) is an infectious disease that affects domestic pig and wild boar populations. The African Swine Fever Virus (ASFV) has a genome characterized by a very complex DNA (170-193 kb) that encodes for more than 200 ...
Rosrio Liberti   +10 more
doaj   +4 more sources

ASFV-G-∆I177L as an Effective Oral Nasal Vaccine against the Eurasia Strain of Africa Swine Fever

open access: yesViruses, 2021
The African swine fever virus (ASFV) is currently causing a pandemic affecting wild and domestic swine from Western Europe to Asia. No commercial vaccines are available to prevent African swine fever (ASF), resulting in overwhelming economic losses to ...
Manuel V Borca   +2 more
exaly   +3 more sources

Evaluation of the Function of ASFV Gene E66L in the Process of Virus Replication and Virulence in Swine

open access: yesViruses, 2023
African swine fever virus (ASFV) is the etiological agent of an economically important disease of swine currently affecting large areas of Africa, Eurasia and the Caribbean.
Elizabeth Ramirez-Medina   +2 more
exaly   +3 more sources

A Rapid p72‐Targeting Colloidal Gold Immunochromatographic Strip for African Swine Fever Virus Detection [PDF]

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF) is a lethal, hemorrhagic, and highly contagious infectious disease caused by the African swine fever virus (ASFV). At present, ASFV has evolved into multiple variant strains with different levels of virulence in China, complicating the epidemiological landscape.
Wan Wang   +14 more
wiley   +2 more sources

African Swine Fever Vaccine Candidate ASFV-G-ΔI177L Produced in the Swine Macrophage-Derived Cell Line IPKM Remains Genetically Stable and Protective against Homologous Virulent Challenge

open access: yesViruses, 2023
ASFV vaccine candidate ASFV-G-ΔI177L has been shown to be highly efficacious in inducing protection against challenges with the parental virus, the Georgia 2010 isolate, as well as against field strains isolated from Vietnam. ASFV-G-ΔI177L has been shown
Ayushi Rai   +2 more
exaly   +3 more sources

CD1D knockout swine are permissive to African swine fever virus genotype II infection [PDF]

open access: yesEmerging Microbes and Infections
African swine fever virus (ASFV) is an important pathogen of domestic and wild suids and the causative agent of African swine fever (ASF). ASFV displays a tropism for myeloid cells, predominately of the monocyte/macrophage lineage, which is critical for ...
Daniel Madden   +15 more
doaj   +2 more sources

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