Results 101 to 110 of about 50,905 (314)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

“A Game of Thrones” – a New Classic?

open access: yesCrossroads, 2013
The following paper depicts George R. R. Martin’s A Game of Thrones as a novel worthy of receiving the title of a classic. Classics are presented as a section of literature to which permission is granted based on particular criteria which is full of ...
Magdalena Łapińska
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Мифология древняя и современная в искусстве и теории искусства

open access: yesИскусство Евразии
Опираясь на работы философов и искусствоведов российского «течения» 1930-х годов М.А. Лифшица и Д. (Георга) Лукача, автор проводит различие между древней и современной мифологией.
Арсланов, В.Г.
doaj   +1 more source

August von Kotzebue et le Siècle de Frédéric II. Histoire d’un succès inachevé

open access: yesCahiers d’Études Germaniques, 2013
After he settled in Berlin in 1802, August von Kotzebue initiated various projects aimed at profiling Prussian culture – and especially that of the capital – and expanding its visibility to a far greater extent.
Klaus Gerlach
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Choosing my major: Classics

open access: yes, 2019
The B.A. in Classics is an interdisciplinary degree focused on the civilizations of the ancient Mediterranean, and can involve the study of ancient Greek and Latin language, literature in translation, history, archaeology and art history.
University of Mississippi. College of Liberal Arts   +2 more
core  

Vergil and Seneca in Consolatio Philosophiae Book 3 [PDF]

open access: yesNew Classicists, 2022
Donald McCarthy
doaj  

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