Results 51 to 60 of about 337,900 (337)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Data‐driven performance metrics for neural network learning

International Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri, Mauro Gaggero, Marcello Sanguineti   +2 more
wiley   +1 more source

Tracking Trends and Brands in the International Children's Book Market

The Journal of Transcultural Studies, 2012
Books are embedded in the culture and language of their origins. Some works may have achieved classic status within their own cultural realm, and yet, even if they have the good fortune to be successfully promoted abroad, they do not necessarily manage ...
Petra Thiel
doaj   +1 more source

On the dynamics of classicalization

Physics Letters B, 2012
We discuss the mechanism through which classicalization may occur during the collapse of a spherical field configuration modelled as a wavepacket. We demonstrate that the phenomenon is associated with the dynamical change of the equation of motion from a second-order partial differential equation of hyperbolic to one of elliptic type.
N. Brouzakis, John Rizos, Nikolaos Tetradis   +2 more
openaire   +3 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Classical Conditioning: Classical Yet Modern

Psychologica Belgica, 2018
This manuscript is part of a special issue to commemorate professor Paul Eelen, who passed away on August 21, 2016. Paul was a clinically oriented scientist, for whom learning principles (Pavlovian or operant) were more than salivary responses and lever presses.
openaire   +6 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Alla scoperta della storia nella musica d’arte: esperienze di analisi percettiva

Musica Docta
In ambito musicale, la trasmissione del sapere deve confrontarsi, soprattutto in Italia, con una diffusa mancanza di preparazione di base anche in contesti formativi di fascia elevata.
Paola Besutti
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

On the Classical Traditions of Azerbaijani Piano Art

Вісник Київського національного університету культури і мистецтв. Серія: Музичне мистецтво
The purpose of the research is to characterise the peculiarities of classical traditions in the history of Azerbaijani piano culture and generalise these traditions.
Ельнара Меджидова
doaj   +1 more source