Results 71 to 80 of about 13,183 (268)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Journal of Open Humanities DataIn this data paper, we argue that computational researchers—particularly those working in low-resource contexts—should consult with linguistic specialists to create targeted stop lists developed with specific eras, genres, authors, or contexts in mind ...
Rachel E. Dubit, Annie K. Lamar
doaj +1 more source
Classical Conditioning: Classical Yet Modern
Psychologica Belgica, 2018 This manuscript is part of a special issue to commemorate professor Paul Eelen, who passed away on August 21, 2016. Paul was a clinically oriented scientist, for whom learning principles (Pavlovian or operant) were more than salivary responses and lever presses.
openaire +5 more sources
Classical Logic, Classical Probability, and Quantum Mechanics [PDF]
, 2020 We give an overview and conceptual discussion of some of our results on contextuality and non-locality. We focus in particular on connections with the work of Itamar Pitowsky on correlation polytopes, Bell inequalities, and Boole's "conditions of possible experience".
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The Spirit of Cocktails: On the Conceptual Structure of Cocktail Recipes
Humana.Mente: Journal of Philosophical Studies, 2020 In this paper, we discuss the conceptual structure of cocktail recipes. This topic involves engaging questions for philosophers and food theorists due to some peculiar characteristics of cocktail recipes, such as the fact that they are standardised by ...
Davide Serpico +2 more
doaj
(Re)Translating as Re-membering
TranscUlturAl, 2016 This paper explores how (re)translation – interlingual and intersemiotic – can be perceived as a way of both remembering the literary legacy of other cultures but also as a way of re-membering/re-generating the body of literature(s) of the importing ...
Julie Tarif
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source