Results 61 to 70 of about 29,880 (316)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
CLASSICS IN GLOBAL HISTORIOGRAPHY: SOME IDEAS IN HISTORICAL PERSPECTIVE
Glocalism: Journal of Culture, Politics and InnovationClassics of historiography are not all the same. As with classics in literature, or in any other human expression, their status depends on both the historical and cultural context within which they were produced and the historical and cultural context ...
Davide Cadeddu
doaj +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Imagining the future of classics pedagogy: an introductory-level, undergraduate course on Medea, intersectionality, and Beloved [PDF]
, 2022 Bridget Farahay
openalex +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
‘Translating’ Classics for Generations Z and Alpha
The Journal of Classics TeachingThis paper presents a public outreach program developed by the Department of Classics at the University of Florida to introduce school-age children to Classics.
Eleni Bozia +2 more
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Classical Political Philosophy and the Crisis of Modernity – An alternative to the competition State
Nordicum-Mediterraneum, 2017 The conservative Jewish, German and American philosopher Leo Strauss (1899-1973) proposes an interpretation of the causes of the crisis of modernity and argues that the only way in which we can reestablish social stability is to go back to classical ...
Jacob Dahl Rendtorff
doaj
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source