Results 71 to 80 of about 209,816 (215)

“Literature as a guide for teaching the Law of God in gymnasiums”: an unwritten article by Priest Konstantin Aggeev [PDF]

open access: yesВестник Свято-Филаретовского института
The article considers the way of shaping literary perceptions of priest Konstantin Aggeev, a prominent figure of the church revival movement of the early twentieth century, apologist and participant of church-cultural dialogue.
Balakshina, Yu. V.
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

Modules Whose Classical Prime Submodules Are Intersections of Maximal Submodules [PDF]

open access: yesarXiv, 2012
Commutative rings in which every prime ideal is the intersection of maximal ideals are called Hilbert (or Jacobson) rings. We propose to define classical Hilbert modules by the property that {\it classical prime} submodules are the intersection of maximal submodules.
arxiv  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Filling the gap between quantum no-cloning and classical duplication [PDF]

open access: yesarXiv, 2018
The correspondence principle suggests that a quantum description for the microworld should be naturally transited to a classical description within the classical limit. However, it seems that there is a large gap between quantum no-cloning and classical duplication.
arxiv  

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

open access: yesMolecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Birkhoff Normal Forms in Semi-Classical Inverse Problems [PDF]

open access: yesarXiv, 2002
We apply recent results on semi-classical trace formulae and on Birkhoff normal forms for semi-classical Fourier integral operators to a wide range of semi-classical and high energy spectral inverse problems.
arxiv  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

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