Results 71 to 80 of about 29,880 (316)

Pia Guldager and Jane Hjar Petersen (eds.), Meetings of cultures in the Black Sea region. Between conflict and coexistence, (Aarhus: Aarhus University Press, 2008)

open access: yesNordicum-Mediterraneum, 2011
Book review of Pia Guldiger's and Jane H. Petersen's Meeting of cultures in the Black Sea region. Between conflict and coexistence (Aarhus: Aarhus University Press, 2008).
Carlo Cantaluppi
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Young Adult, Classics and Fiction for Adults: What First-Year Student Teachers of English Choose to Read

open access: yesCLELEjournal
In this contribution the author reports on her study of student teachers’ own reading interests when reading for pleasure, which found university students preferred fiction for adult readers rather than fiction marketed for adolescent readers, and many ...
Melissa Kennedy
doaj  

Maria Sommer & Dion Sommer, Care, Socialization and Play in Ancient Attica. A Developmental Childhood Archaeological Approach (Aarhus: Aarhus University Press, 2015)

open access: yesNordicum-Mediterraneum, 2016
Book review of: Maria Sommer & Dion Sommer, Care, Socialization and Play in Ancient Attica. A Developmental Childhood Archaeological Approach (Aarhus: Aarhus University Press, 2015)
Kristina Egumenovska
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Classical harmony.

open access: yesNotre Dame Journal of Formal Logic, 1986
The author considers a natural deduction formulation of the classical first-order predicate logic and introduces the corresponding inversion principle.
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

“Orpheus’ Sermon”: Making a Case for an Antiquer Dickinson

open access: yesTransatlantica, 2016
The article discusses Dickinson as seizing upon the classics and the Latin language as correctives to the long lasting impact of Calvinism upon her cultural environment.
Eric Athenot
doaj   +1 more source

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