Results 91 to 100 of about 4,952,791 (292)

Development of a Smart Chair Sensors System and Classification of Sitting Postures with Deep Learning Algorithms [PDF]

open access: gold, 2022
Taraneh Aminosharieh Najafi   +3 more
openalex   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Inside the nation’s largest mental health institution: a prevalence study in a state prison system

open access: yesBMC Public Health, 2017
Background The United States has the highest incarceration rate in the world which has created a public health crisis. Correctional facilities have become a front line for mental health care.
Tala Al-Rousan   +4 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Drought effects on the floristic differentiation of Greek fir forests in the mountains of central Greece

open access: yesiForest - Biogeosciences and Forestry, 2015
Greek fir (Abies cephalonica Loudon) grows in montane Mediterranean climates characterized by dry, warm summers. Drought is an important climatic feature of these montane ecosystems as it affects the floristic composition, structure and distribution of ...
Samaras Dimitrios A   +3 more
doaj   +1 more source

Oral health by obesity classification in young obese women – a cross-sectional study [PDF]

open access: diamond, 2022
Negin Taghat   +5 more
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Multilayer Hybrid Deep-Learning Method for Waste Classification and Recycling [PDF]

open access: hybrid, 2018
Yinghao Chu   +5 more
openalex   +1 more source

Fast Pasture Classification Method using Ground-based Camera and the Modified Green Red Vegetation Index (MGRVI) [PDF]

open access: diamond, 2023
Boris Evstatiev   +8 more
openalex   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

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