Results 91 to 100 of about 2,596,382 (316)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
, 2016 The systematic arrangement of empirical evidence is the necessary premise of any archaeological enquiry. If the process that generated an observed pattern has to be investigated, archaeologists need to choose scales and units of analysis that are appropriate for their specific context and the relative research questions.
openaire +3 more sources
Study on sloshing simulation in the independent tank for an ice-breaking LNG carrier
International Journal of Naval Architecture and Ocean Engineering, 2020 As the LNG carrier operates in ice covered waters, it is key to ensure the overall safety, which is related to the coupling effect of ice-breaking process and internal liquid sloshing. This paper focuses on the sloshing simulation of the ice-breaking LNG
Shifeng Ding, Gang Wang, Qiuming Luo
doaj
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Classification of papillomaviruses
Virology, 2004 One hundred eighteen papillomavirus (PV) types have been completely described, and a yet higher number of presumed new types have been detected by preliminary data such as subgenomic amplicons. The classification of this diverse group of viruses, which include important human pathogens, has been debated for three decades.
Ethel Michele De Villiers +4 more
openaire +2 more sources
ASSESSMENT OF LIBRARY USERS’ FEEDBACK USING MODIFIED MULTILAYER PERCEPTRON NEURAL NETWORKS
ICTACT Journal on Soft Computing, 2017 An attempt has been made to evaluate the feedbacks of library users of four different libraries by using neural network based data mining techniques. This paper presents the results of a survey of users’ satisfactory level on four different libraries ...
K G Nandha Kumar, T Christopher
doaj +1 more source