Results 211 to 220 of about 6,126,485 (362)
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Double-stage insect recognition model based on synergistic localization of key parts. [PDF]
Chen D +4 more
europepmc +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Commentary on "The Classification of Nerve Injury Revisited: Sundland 0-VI": Toward a Roadmap for Surgical Decision Making in Nerve Injury. [PDF]
Krauss EM.
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Drug Recognition and Evaluation regions [PDF]
No relief shown.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon ...
core
Brain Tumor Classification and Segmentation in MR Images Using EfficientNet and U-Net++ Models. [PDF]
Alkharaan R +3 more
europepmc +1 more source
Textural Features for Image Classification
R. Haralick, K. Shanmugam, I. Dinstein
semanticscholar +1 more source

