Results 211 to 220 of about 6,795,342 (412)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Reliability and clinical utility of paediatric ankle fracture classifications : a systematic review. [PDF]

open access: yesBone Jt Open
Teo LS   +6 more
europepmc   +1 more source

Official classification and pay plans, Government of Newfoundland and Labrador

open access: yes, 1974
Official Classification and Pay Plans Government of Newfoundland and Labrador 1974General information -- Alphabetic listing of position classifications -- Salary scales for general service group -- Salary scales for nursing group -- Salary scales for ...
Newfoundland. Treasury Board. Classification and Pay Division
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Rational descriptive classification of duricrusts

open access: yes, 1969
The term duricrust appears to be extending itself to include calcareous, gypseous, and saline crusts, in addition to crusts composed dominantly of silica and/or of sesquioxides of iron and aluminium, with or without significant contents of dioxides of ...
Dury, G.H.
core  

ImageNet classification with deep convolutional neural networks

open access: yesCommunications of the ACM, 2012
A. Krizhevsky   +2 more
semanticscholar   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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