Results 201 to 210 of about 6,126,485 (362)

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Automated classification of natural habitats using ground-level imagery. [PDF]

PLoS One
Tourian M, Vandaele R, Rowlands S, Fancourt M, Mein R, Hadfield B, Saunders A, Potter S, Woodget A, Williams HTP.   +9 more
europepmc   +1 more source

ImageNet classification with deep convolutional neural networks

Communications of the ACM, 2012
A. Krizhevsky, I. Sutskever, Geoffrey E. Hinton   +2 more
semanticscholar   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

The Peaceful Pill Handbook Refused Classification Upon Review [PDF]

, 2007

core  

Author Response to Letter on “Blood Pressure and Hypertension in Adolescents and Young Adults: Results From a Nationwide Screening Program”

The Journal of Clinical Hypertension
Wesley Teck Wee Loo, Wilbert Hsien Hao Ho, Daniel Yan Zheng Lim, Nishanth Thiagarajan, Wee Kiat Ang, Jonathan Yong Jun Han, Shen Goy, Gerald Gui Ren Sng, Lian Kiat Lim, Huai Yang Lim   +9 more
doaj   +1 more source

An AI-driven framework for diabetic foot ulcer classification, segmentation, and depth estimation. [PDF]

Sci Rep
Debnath S, Willson D, N RM, S SH, Kishore J, Singh R.   +5 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Voice disorders classification using machine learning: a scoping review. [PDF]

Front Digit Health
Gupta R, Jin CT, Gunjawate DR, Nguyen DD, Stasak B, Chacon AM, Madill C.   +6 more
europepmc   +1 more source