Results 181 to 190 of about 6,126,485 (362)

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

open access: yesActa Neuropathologica, 2016
D. Louis   +9 more
semanticscholar   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

Weblogs Content Classification Tools: performance evaluation [PDF]

open access: yes, 2006
Nowadays, weblogs or blogs are important tools for personal or workgroup websites publication. These tools give the necessary performances to create, edit, evaluate, publish and file digital contents, in the framework of a standarized workflow, and for ...
Tramullas, Jesús   +3 more
core  

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.

open access: yesBlood, 2016
D. Arber   +8 more
semanticscholar   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Acquisition and QC for classification of digital chest radiographs : Group discussion and outcome [PDF]

open access: yes
cdc:131061Group discusion at the NIOSH Scientific Workshop : Application of the ILO International Classification of Radiographs of Pneumoconioses to Digital Chest Radiographic Images (2008 : Mar 12-13 : Washington ...

core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Enhancing classification performance over noise and imbalanced data problems [PDF]

open access: yes, 2012
This research presents the development of techniques to handle two issues in data classification: noise and imbalanced data problems. Noise is a significant problem that can degrade the quality of training data in any learning algorithm.
Jeatrakul, Piyasak
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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