Results 281 to 290 of about 10,572,234 (361)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Automated Classification of Lymphoma Subtypes From Histopathological Images Using a U-Net Deep Learning Model: Comparative Evaluation Study.

JMIR Med Inform
Zhao J, Wen X, Ma L, Su L.
europepmc   +1 more source

Distal Radius Fracture Classifications in Real Life: Reliability and How They Change Treatment. [PDF]

J Hand Surg Glob Online
Nguyen SA, Dang AH, Tran DQ.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A hybrid model for improved nail disease classification using vision transformers and stable diffusion. [PDF]

Sci Rep
Nijhawan R, Gupta A, Diwakar M, Singh P, Bijalwan A.   +4 more
europepmc   +1 more source

Development of an Image Recognition System Based on Neural Networks for the Classification of Plant Species in the Amazon Rainforest, Peru, 2024

Brian Meneses-Claudio
openalex   +1 more source

Dimensionality reduction by minimizing nearest-neighbor classification error

, 2010
Mauricio Villegas, Roberto Paredes
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Tackling High Dimensionality in QSP: Guiding Model Order Reduction With Index Analysis. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tillil J, Huisinga W, Knöchel J.
europepmc   +1 more source

A case-study of NIRS application for infant cerebral hemodynamic monitoring: A report of data analysis for feature extraction and infant classification into healthy and unhealthy

, 2018
Ali Rahimpour, Hosein Ahmadi Noubari, Mohammad Kazemian   +2 more
openalex   +1 more source