Results 11 to 20 of about 6,147 (145)
Generic Model Refactorings [PDF]
, 2009 Many modeling languages share some common concepts and principles. For example, Java, MOF, and UML share some aspects of the concepts\ud of classes, methods, attributes, and inheritance.
B.C.D.S. Oliveira +17 more
core +6 more sources
Early aspects: aspect-oriented requirements engineering and architecture design [PDF]
, 2004 This paper reports on the third Early Aspects: Aspect-Oriented Requirements Engineering and Architecture Design Workshop, which has been held in Lancaster, UK, on March 21, 2004.
Araújo, João +3 more
core +11 more sources
Diagnosis of the significance of inconsistencies in software designs: a framework and its experimental evaluation [PDF]
, 2002 This paper presents: (a) a framework for assessing the significance of inconsistencies which arise in object-oriented design models that describe software systems from multiple perspectives, and (b) the findings of a series of experiments conducted to ...
Chidamber +20 more
core +1 more source
Integrating security and usability into the requirements and design process [PDF]
, 2006 According to Ross Anderson, 'Many systems fail because their designers protect the wrong things or protect the right things in the wrong way'. Surveys also show that security incidents in industry are rising, which highlights the difficulty of designing ...
Flechais, I, Mascolo, C, Sasse, MA
core +1 more source
Event-driven grammars: Relating abstract and concrete levels of visual languages [PDF]
, 2007 The final publication is available at Springer via http://dx.doi.org/10.1007/s10270-007-0051-2In this work we introduce event-driven grammars, a kind of graph grammars that are especially suited for visual modelling environments generated by meta ...
Guerra, Esther, Lara, Juan de
core +2 more sources
Refactoring OCL annotated UML class diagrams [PDF]
, 2005 Refactoring of UML class diagrams is an emerging research topic and heavily inspired by refactoring of program code written in object-oriented implementation languages. Current class diagram refactoring techniques concentrate on the diagrammatic part but
Baar, Thomas, Marković, Slaviša
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Supporting process reuse in PROMENADE [PDF]
, 2002 Process reuse (the ability to construct new processes by assembling already built ones) and process harvesting (the ability to build generic processes that may be further reused, from existing ones) are two crucial issues in process technology.
Franch Gutiérrez, Javier +1 more
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source