Results 91 to 100 of about 197,388 (314)

Study on Residual Defect Prediction using Multiple Technologies

open access: yesJournal of Advances in Information Technology, 2014
Finding defects in a software system is not easy. Effective detection of software defects is an important activity of software development process.
Wanjiang Han   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Using multiple and negative target rules to make classifiers more understandable

open access: yes, 2006
[Abstract]: One major goal for data mining is to understand data. Rule based methods are better than other methods in making mining results comprehensible.
Li, Jiuyong   +5 more
core   +1 more source

Subclass problem-dependent design for error-correcting output codes [PDF]

open access: yes, 2008
A common way to model multiclass classification problems is by means of Error-Correcting Output Codes (ECOCs). Given a multiclass problem, the ECOC technique designs a code word for each class, where each position of the code identifies the membership of
Radeva, Petia   +4 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

[Newsletter] [PDF]

open access: yes, 2019
This newsletter from the Soil Classifiers Advisory Council gives information about the Council including professional licenses for soil classifiers, office hours and state holidays, council members and staff and online ...
South Carolina Soil Classifiers Advisory Council
core  

Effective Intrusion Detection System Using XGBoost

open access: yesInformation, 2018
As the world is on the verge of venturing into fifth-generation communication technology and embracing concepts such as virtualization and cloudification, the most crucial aspect remains “security”, as more and more data get attached to the ...
Sukhpreet Singh Dhaliwal   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Analysis of the Correlation Between Majority Voting Error and the Diversity Measures in Multiple Classifier Systems

open access: yes, 2001
Combining classifiers by majority voting (MV) has recently emerged as an effective way of improving performance of individual classifiers. However, the usefulness of applying MV is not always observed and is subject to distribution of classification ...
Ruta, Dymitr, Gabrys, Bogdan
core  

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