Results 301 to 310 of about 126,267 (387)

Bypassing Endocytic Barriers: Visualizing Membrane Fusion and Endosomal Escape of Cubic Phase Lipid Nanoparticles (Cubosomes)

Small, EarlyView.
This study uses advanced microscopy techniques, including transmission electron microscopy, scanning electron microscopy (SEM), cryogenic SEM, and live‐cell fluorescence imaging, to investigate lipid cubosome interactions with mammalian cells. It provides the first direct nanoscale evidence of cubosome membrane fusion with plasma and endosomal ...
Sue Lyn Yap, Chaitali Dekiwadia, Enrico Della Gaspera, Calum J. Drummond, Charlotte E. Conn, Nhiem Tran   +5 more
wiley   +1 more source

Retraction for Austin et al., Death-receptor activation halts clathrin-dependent endocytosis. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Regulation of clathrin assembly and trimerization defined using recombinant triskelion hubs

, 1995
Shu‐Hui Liu, Mei Lie Wong, Charles S. Craik, Frances M. Brodsky   +3 more
openalex   +1 more source

Inhibition of the Clathrin Terminal Domain-Amphiphysin Protein-Protein Interaction. Probing the Pitstop 2 Aromatic Moiety. [PDF]

ChemMedChem
Prichard K, Robertson MJ, Chau N, Xue J, Neuenschwander M, Fink U, Horatscheck A, Nazare M, Robinson PJ, Haucke V, McCluskey A.   +10 more
europepmc   +1 more source

Native Taylor/Non‐Taylor Dispersion–Mass Spectrometry (TNT‐MS) Allows Rapid Protein Desalting and Multiplexed, Label‐Free Ligand Screening

Small Methods, EarlyView.
Native mass spectrometry enables the label‐free study of noncovalent protein‐ligand complexes; however, it is incompatible with conventional molecular biology buffers. By exploiting the dependence of flow dynamics on the hydrodynamic radius, proteins are seperated, including protein‐ligand complexes, from non‐volatile salts and unbound small molecules ...
Jonathan Eisert, Edvaldo Vasconcelos Soares Maciel, Verena Dederer, Aylin Berwanger, Henry J. Bailey, Ivan Đikić, Stefan Knapp, Martin Empting, Sebastian Mathea, Henrik Jensen, Frederik Lermyte   +10 more
wiley   +1 more source

Host-Pathogen Cellular Communication: The Role of Dynamin, Clathrin, and Macropinocytosis in the Uptake of Giardia-Derived Extracellular Vesicles. [PDF]

ACS Infect Dis
Sabatke B, Rossi IV, Bonato L, Fucio S, Cortés A, Marcilla A, Ramirez MI.   +6 more
europepmc   +1 more source

Phenothiazine‐Derived Antipsychotic Drugs Inhibit Dynamin and Clathrin‐Mediated Endocytosis

Traffic : the International Journal of Intracellular Transport, 2015
James A Daniel, Ngoc Chau, Mohammed K. Abdel-Hamid, Li-Che Hu, L. von Kleist, Ainslie Whiting, Sai Krishnan, P. Maamary, Shannon R. Joseph, Fiona Simpson, V. Haucke, A. McCluskey, P. Robinson   +12 more
semanticscholar   +1 more source

Nanotechnology and cell death: Revolutionizing disease treatment with nanoparticle strategies

VIEW, EarlyView.
Traditional disease treatments often face issues such as poor drug targeting and significant side effects, with many complex diseases lacking effective therapies. Our research utilizes tiny nanomaterials to treat diseases by regulating natural cell death processes, improving the immune environment, etc., enabling drugs to act more precisely.
Yiwen Wan, Wangzheqi Zhang, Yan Liao, Chenglong Zhu, Xiaojing Guo, Zui Zou, Mi Li   +6 more
wiley   +1 more source

Mdm2-Mediated Ubiquitination Plays a Pivotal Role in Differentiating the Endocytic Roles of GRK2 and Arrestin3. [PDF]

Int J Mol Sci
Wang S, Kundu D, Zhang X, Tian X, Peng L, Kim KM.   +5 more
europepmc   +1 more source

Quantifying Cytotoxicity and Cellular Uptake of Naked Gold Nanoparticles Using Total Reflection X‐Ray Fluorescence

X-Ray Spectrometry, EarlyView.
ABSTRACT The study of the cytotoxic effects of gold nanoparticles (AuNP) is an active area of research. However, there is a lack of consistency in results with measures of cellular uptake relying on inductively coupled plasma (ICP)‐based methods, which introduce inconsistencies with sample preparation.
Natasha Hedden, Gabriela Traplin, Gabriella Mankovskii, Raffi Karshafian, Michael Kolios, Ana Pejovic‐Milic   +5 more
wiley   +1 more source