Results 311 to 320 of about 126,267 (387)

Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks

Malady BT, Papagiannoula A, Kamatar A, Sarkar S, Lebrun GT, Wang L, Hayden CC, Lafer EM, Owen DJ, Milles S, Stachowiak JC.   +10 more
europepmc   +1 more source

The role of transcytosis in the blood-retina barrier: from pathophysiological functions to drug delivery. [PDF]

Front Pharmacol
Zhang CL, Ma JJ, Li X, Yan HQ, Gui YK, Yan ZX, You MF, Zhang P.   +7 more
europepmc   +1 more source

Cell‐Surface LAMP1 is a Senescence Marker in Aging and Idiopathic Pulmonary Fibrosis

Aging Cell, EarlyView.
We have validated the selective upregulation of LAMP1 in SEN in culture, and the percentage of Lamp1+ cells increases in various tissues with age, as well as in fibrotic lungs following BLM instillation. The RNA‐Sequencing analysis of the Lamp1‐enriched populations confirmed the enrichment of senescence‐related genes.
Gabriel Meca‐Laguna, Michael Qiu, Yafei Hou, Anna Barkovskaya, Apoorva Shankar, Bhavna Dixit, Michael J. Rae, Amutha Boominathan, Amit Sharma   +8 more
wiley   +1 more source

Beyond Clathrin: Decoding the Mechanism of Ultrafast Endocytosis. [PDF]

Physiology (Bethesda)
Imoto Y, Watanabe S.
europepmc   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Sweet control: intracellular sorting of glycoproteins in plants. [PDF]

J Exp Bot
Qi W, Zhang B, Yue J, Zhang L.
europepmc   +1 more source

CTCF Is Essential for the Development and Maintenance of CALM‐AF10‐Induced Leukemia

Cancer Science, EarlyView.
CTCF regulates TGM2 gene expression by modulating key histone modifications, including increased acetylation of H3K27 (H3K27ac) and trimethylation of H3K4 (H3K4me3), along with decreased trimethylation of H3K27 (H3K27me3). These epigenetic changes are critical for maintaining the stem‐like properties of CALM‐AF10‐induced AML. Pharmacological inhibition
Yoko Kuroki, Kazutsune Yamagata, Yukiko Aikawa, Yutaka Shima, Hisafumi Shioneri, Issay Kitabayashi   +5 more
wiley   +1 more source

Transferrin receptor 1 (TfR1) functions as an entry receptor for scale drop disease virus to invade the host cell via clathrin-mediated endocytosis. [PDF]

J Virol
Chen J, Fu Y, Li Y, Weng S, Wang H, He J, Dong C.   +6 more
europepmc   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Promiscuous and multivalent interactions between Eps15 and partner protein Dab2 generate a complex interaction network. [PDF]

Nat Commun
Papagiannoula A, Vedel IM, Motzny K, Tengo M, Saiti A, Milles S.   +5 more
europepmc   +1 more source