Results 51 to 60 of about 16,294 (235)

PM10 Impairs CD56dim NK Cell Cytotoxicity via FNBP1 Suppression to Exacerbate Rheumatoid Arthritis: Insights from Multimodal Multi‐Omics

Advanced Science, EarlyView.
This study, through multi‐omics approaches and animal models, revealed that air pollutant PM10 exacerbates the progression of rheumatoid arthritis (RA) by suppressing FNBP1 expression and impairing the cytotoxic function of CD56dim NK cells. The “PM10–FNBP1–NK cells” axis provided novel insights into the environmental pathogenesis of RA and suggested ...
Runhan Zhao, Qinyang Zhang, Yu Jiang, Dagang Tang, Xiao Qu, Jun Zhang, Yi Chen, Weixia Duan, Tao Li, Zhengwei Cai, Yanran Huang, Xiaoji Luo   +11 more
wiley   +1 more source

Genetic relationships between claw health traits of dairy cows in different parities, lactation stages, and herds with different claw disorder frequencies [PDF]

Journal of Dairy Science, 2015
Claw disorders affect cow welfare and profitability of farms. Not only claw disorders but also the need for trimming, known as trimming status, has been shown to be heritable. Limited knowledge is available on whether claw health traits (claw disorders and trimming status) are genetically the same trait in different parities, lactation stages, or in ...
van der Spek, D., van Arendonk, J.A.M., Bovenhuis, H.   +2 more
openaire   +3 more sources

Genetic variation in dairy cattle claw health traits recorded by claw trimmers [PDF]

, 2013
Claw health has been recorded by claw trimmers at trimming in Sweden since 1996, but data was then captured at each AI association. From 2003 data was captured by central scanning and entered directly to the national cow data base at the Swedish Dairy ...
Naeslund, Sandra
core   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Evaluation of Claw Lesions in Beef Cattle Slaughtered in Northern Portugal: A Preliminary Study

Animals
Claw diseases have a profound impact on cattle welfare, affecting behaviors such as grazing, rumination, rest, decubitus, and water consumption. This study aimed to assess the prevalence of claw lesions and classify them according to the ICAR Claw Health
Mafalda Seixas, Dina Moura, Luca Grispoldi, Beniamino Cenci-Goga, Sónia Saraiva, Filipe Silva, Isabel Pires, Cristina Saraiva, Juan García-Díez   +8 more
doaj   +1 more source

Genetic parameters for claw disorders and the effect of preselecting cows for trimming [PDF]

Journal of Dairy Science, 2013
Claw disorders are important traits relevant to dairy cattle breeding from an economical and welfare point of view. Selection for reduced claw disorders can be based on hoof trimmer records. Typically, not all cows in a herd are trimmed. Our objectives were to estimate heritabilities and genetic correlations for claw disorders and investigate the ...
van der Spek, D., van Arendonk, J.A.M., Vallee, A.A.A., Bovenhuis, H.   +3 more
openaire   +2 more sources

Early evolutionary history of the seed

Biological Reviews, EarlyView.
ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman, Alan R. T. Spencer, Jason Hilton   +2 more
wiley   +1 more source

The most common reproductive disorders of cows in Holstein cattle breeding

Czech Journal of Animal Science, 2023
The paper deals with the genomic evaluation of retained placenta (RP), metritis/endometritis (MET), and cystic ovarian disease (CYS) and their involvement in the selection programme of Holstein cattle. A procedure for the estimation of genetic parameters
Eva Kašná, Ludmila Zavadilová, Zuzana Krupová, Soňa Šlosárková, Petr Fleischer   +4 more
doaj   +1 more source

Genetic Parameters for Claw Disorders in Dutch Dairy Cattle and Correlations with Conformation Traits [PDF]

Journal of Dairy Science, 2005
Impaired claw health is one of the major problems causing production loss and reduced animal welfare in dairy cattle. In response, the Dutch Animal Health Service (GD) Ltd. initiated this study, in which claws of lactating and near-term cows and heifers in 430 herds were trimmed by hoof trimmers and the health status of the rear claws recorded.
van der Waaij, E.H., Holzhauer, M., Ellen, E.D., Kamphuis, C., de Jong, G.   +4 more
openaire   +3 more sources

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source