Results 41 to 50 of about 1,114,301 (265)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Clean Ocean Advocate, November 2007
, 2007 The monthly Clean Ocean Advocate newsletter informs citizens about critical ocean pollution issues, important meeting dates, proposed legislation, special events, and other notes of interest.
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Clean Ocean Advocate, July 2007
, 2007 The monthly Clean Ocean Advocate newsletter informs citizens about critical ocean pollution issues, important meeting dates, proposed legislation, special events, and other notes of interest.
core +1 more source
Proceedings, 2020 Starting clean and staying clean is one of the simplest ways to maximise. [...]
Mark Whattam
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Clean Ocean Advocate, May 2009
, 2009 The monthly Clean Ocean Advocate newsletter informs citizens about critical ocean pollution issues, important meeting dates, proposed legislation, special events, and other notes of interest.
core +1 more source
Advances in Polymer Technology, 2021 Chitosan-based intelligent artificial systems have been of increasing interest for their biocompatibility, multifunctionality, biological activity, and low cost.
An Liu +5 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Clean Ocean Advocate, March 2007
, 2007 The monthly Clean Ocean Advocate newsletter informs citizens about critical ocean pollution issues, important meeting dates, proposed legislation, special events, and other notes of interest.
core +1 more source