Results 61 to 70 of about 1,114,301 (265)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Clean Ocean Advocate, December 2008

, 2008
The monthly Clean Ocean Advocate newsletter informs citizens about critical ocean pollution issues, important meeting dates, proposed legislation, special events, and other notes of interest.

core   +1 more source

Analysis of early fault vibration detection and analysis of offshore wind power transmission based on deep neural network

Connection Science, 2022
Among the main fault locations of wind turbines, downtime accidents caused by bearing faults account for the majority. Therefore, it is of practical significance to detect the fault signal of the fan bearing as early as possible, and to arrange the ...
Boyu Yang, Anmin Cai, Weirong Lin
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Clean Ocean Advocate, December 2007

, 2007
The monthly Clean Ocean Advocate newsletter informs citizens about critical ocean pollution issues, important meeting dates, proposed legislation, special events, and other notes of interest.

core   +1 more source

Training and assistance in clean water treatment for communities to meet hygienic water needs

Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang
Yobeh Village, located in the Sentani district, consisted of 3 community units (RW) and 7 neighborhood units (RT) with a total of 173 families and 692 residents. A portion of the community, approximately 56 families with around 246 residents, lived along
Bambang Suhartawan, Suyatno Suyatno, Alfred Benjamin Alfons, Andrea Karina Marielle P. Abel, Katherina T. J. Mayor Sroyer   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Clean Ocean Advocate, May 2007

, 2007
The monthly Clean Ocean Advocate newsletter informs citizens about critical ocean pollution issues, important meeting dates, proposed legislation, special events, and other notes of interest.

core   +1 more source

Assessing the Impact of Battery Electric Vehicles (BEVs) Adoption on Air Quality and Public Health in Indonesia [PDF]

E3S Web of Conferences
Indonesia faces a major challenge in reducing transport emissions, which contribute significantly to air pollution and increased potential for health risks. Battery Electric Vehicle (BEV) adoption is one of the national strategies to reduce emission from
Ghaida Azka, Ningsih Almira Solehah, Dewati Regyna Elrica, Muharrami Revia, Permadi Didin Agustian, Goyal Prachi, Kusuma Ririn Radiawati   +6 more
doaj   +1 more source