Results 31 to 40 of about 276,191 (223)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The strong nil-cleanness of semigroup rings
Open Mathematics, 2020 In this paper, we study the strong nil-cleanness of certain classes of semigroup rings. For a completely 0-simple semigroup M=ℳ0(G;I,Λ;P)M={ {\mathcal M} }^{0}(G;I,\text{Λ};P), we show that the contracted semigroup ring R0[M]{R}_{0}{[}M] is ...
Ji Yingdan
doaj +1 more source
Addendum: A Note on Commutative Nil-Clean Corners in Unital Rings
Известия Иркутского государственного университета: Серия "Математика", 2020 The author wish to add the following to the Acknowledgement section of this Article ”The author would like to express his sincere thanks to Dr. Janez Ster from University of Ljubljana for their joint communication on the subject of the paper and valuable
P.V. Danchev
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
J~#-Uc cleanness and strongly J~#-Uc cleanness of rings
Nantong Daxue xuebao. Ziran kexue banA ring R is GU_cJ if U(R)=Uc(R)+J~#(R);R is (strongly) J~#-U_c-clean ring if for any a∈R,there exists g∈Uc(R),p2=p∈R,d∈J~#(R),such that ag=p+d (and ap=pa).GU_cJ rings and J~#-U_c-clean rings are proper generalizations of GUJ rings and GJ-clean rings ...
JIN Danya; HUANG Tao; CUI Jian
doaj +1 more source
Tripotents: a class of strongly clean elements in rings
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2018 Periodic elements in a ring generate special classes of strongly clean elements. In particular, elements b such that b = b3+, which are called tripotents and include idempotents, negative of idempotents and order 2 units, are strongly clean.
Călugăreanu Grigore
doaj +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Some properties of skew Hurwitz series
Le Matematiche, 2014 In this paper we show that, if R is a ring and σ an endomorphism of R, then the skew Hurwitz series ring T = (HR, σ ) is an n-clean ring if and only if R is an n-clean ring.
A. M. Hassanein, Mohamed A. Farahat
doaj
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source