Results 41 to 50 of about 276,191 (223)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Rings in which elements are the sum of a nilpotent and a root of a fixed polynomial that commute
Open Mathematics, 2017 An element in a ring R with identity is said to be strongly nil clean if it is the sum of an idempotent and a nilpotent that commute, R is said to be strongly nil clean if every element of R is strongly nil clean. Let C(R) be the center of a ring R and g(
Handam Ali H., Khashan Hani A.
doaj +1 more source
A Note on Commutative Nil-Clean Corners in Unital Rings
Известия Иркутского государственного университета: Серия "Математика", 2019 We shall prove that if $R$ is a ring with a family of orthogonal idempotents $\{e_i\}_{i=1}^n$ having sum $1$ such that each corner subring $e_iRe_i$ is commutative nil-clean, then $R$ is too nil-clean, by showing that this assertion is actually ...
P.V. Danchev
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Rings in Which Element is a Sum of the Transformation Elements of Idempotents and Special Elements
Journal of MathematicsIn this article, further generalizations are made for the nil clean ring and the ur-clean ring, obtained as extensions of the clean ring. Firstly, consider rings where each element can be expressed as n idempotents plus one nilpotent, any two commute ...
Xinsong Yang, Jiaxin Liu
doaj +1 more source
The Strongly Nil-Clean Rings Of Order Two Units [PDF]
Al-Rafidain Journal of Computer Sciences and MathematicsIf every element of a ring R is the sum of idempotent and nilpotent that commute, then the ring is said to be a strongly nil-clean. Further features of a strongly nil-clean ring are given in this paper.
Samira Toma, Nazar Shuker
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FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Trivial Ring Extension of Suitable-Like Conditions and some properties [PDF]
مجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2018 We investigate the transfer of the notion of suitable rings along with related concepts, such as potent and semipotent rings, in the general context of the trivial ring extension, then we put these results in use to enrich the literature with new ...
Khalid Adarbeh
doaj +1 more source