Results 21 to 30 of about 375,248 (265)

Predicted Potential for Aquatic Exposure Effects of Per- and Polyfluorinated Alkyl Substances (PFAS) in Pennsylvania’s Statewide Network of Streams

Toxics
Per- and polyfluoroalkyl substances (PFAS) are contaminants that can lead to adverse health effects in aquatic organisms, including reproductive toxicity and developmental abnormalities. To assess the ecological health risk of PFAS in Pennsylvania stream
Sara E. Breitmeyer, Amy M. Williams, Matthew D. Conlon, Timothy A. Wertz, Brian C. Heflin, Dustin R. Shull, Joseph W. Duris   +6 more
doaj   +1 more source

Uji Kelayakan Air Minum Di Desa Kampung Pinang Kecamatan Perhentian Raja Kabupaten Kampar

Dinamisia, 2023
Water is a natural resource that is absolutely necessary for life and human life, as well as in the environmental management system, water is the main element.
Harmiyati Harmiyati, Tessa Shasrini, Sy. Sarah Alwiah, Athasyafa Ramadhan, Gryanda Wahyu Sugeng   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Making the invisible visible: results of a community-led health survey following PFAS contamination of drinking water in Merrimack, New Hampshire

Environmental Health, 2019
Background In March 2016, citizens of Merrimack, New Hampshire, learned that their public water supply was contaminated with perfluorooctanoic acid (PFOA).
Bindu Panikkar, Benjamin Lemmond, Laurene Allen, Carol DiPirro, Shaina Kasper   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Research progress on control technologies of organic pollutants in coal mining water

Gongye shui chuli
The protection and utilization of coal mining water resources is an important part of coal green development of China. There are many kinds of organic pollutants in mining water, and the research on their source, migration path and control technology in ...
HU Jiamin, BAO Yixiang, WU Min, WANG Jingyu, HE Ruimin   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The influence of cyclic loading-unloading rates on the uniaxial mechanical anisotropy of coal

Scientific Reports
In this study, the influence of the loading-unloading rate on the uniaxial mechanical anisotropy of coal was investigated via uniaxial compressive tests, acoustic emission (AE) monitoring, digital image correlation (DIC), and a series of coal specimens ...
Duo Xu, Honghua Song, Like Zhao, Guoqing Tang, Shide Hu, Chenxi Duan, Yunting Song   +6 more
doaj   +1 more source

Potential Evaluation of Cross-Seasonal Heat Storage of Coal Mine Underground Reservoir: A Case Study Based on Multiphysics Coupling Numerical Simulation Method

Applied Sciences
This study explores the innovative use of post-mining subsurface voids by proposing a coal mine goaf-based underground reservoir energy storage system. By fully utilizing the geothermal potential and insulation properties of the mined-out coal seam, we ...
Zhenyu Wang, Jiawei Tang, Zixu Hu, Qiang Guo, Haiqin Zhang, Kangning Zhang, Siwei Kang, Xiaolin He   +7 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source