Results 21 to 30 of about 377,718 (265)

Research progress on control technologies of organic pollutants in coal mining water

Gongye shui chuli
The protection and utilization of coal mining water resources is an important part of coal green development of China. There are many kinds of organic pollutants in mining water, and the research on their source, migration path and control technology in ...
HU Jiamin, BAO Yixiang, WU Min, WANG Jingyu, HE Ruimin   +4 more
doaj   +1 more source

Making the invisible visible: results of a community-led health survey following PFAS contamination of drinking water in Merrimack, New Hampshire

Environmental Health, 2019
Background In March 2016, citizens of Merrimack, New Hampshire, learned that their public water supply was contaminated with perfluorooctanoic acid (PFOA).
Bindu Panikkar, Benjamin Lemmond, Laurene Allen, Carol DiPirro, Shaina Kasper   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Predicted Potential for Aquatic Exposure Effects of Per- and Polyfluorinated Alkyl Substances (PFAS) in Pennsylvania’s Statewide Network of Streams

Toxics
Per- and polyfluoroalkyl substances (PFAS) are contaminants that can lead to adverse health effects in aquatic organisms, including reproductive toxicity and developmental abnormalities. To assess the ecological health risk of PFAS in Pennsylvania stream
Sara E. Breitmeyer, Amy M. Williams, Matthew D. Conlon, Timothy A. Wertz, Brian C. Heflin, Dustin R. Shull, Joseph W. Duris   +6 more
doaj   +1 more source

Clean Water User Behavior for Clean Water Savings in Topoyo Mamuju

IOP Conference Series: Earth and Environmental Science, 2021
Abstract The purpose of this study is to analyze people’s behavior in using clean water based on their water source and the factors that influence that behavior. This research method through data collection is done by observing the level of education, type of work, income level, number of people, analysis of the relationship between ...
D Musa, S Trisutomo, A Akil
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

The influence of cyclic loading-unloading rates on the uniaxial mechanical anisotropy of coal

Scientific Reports
In this study, the influence of the loading-unloading rate on the uniaxial mechanical anisotropy of coal was investigated via uniaxial compressive tests, acoustic emission (AE) monitoring, digital image correlation (DIC), and a series of coal specimens ...
Duo Xu, Honghua Song, Like Zhao, Guoqing Tang, Shide Hu, Chenxi Duan, Yunting Song   +6 more
doaj   +1 more source

Potential Evaluation of Cross-Seasonal Heat Storage of Coal Mine Underground Reservoir: A Case Study Based on Multiphysics Coupling Numerical Simulation Method

Applied Sciences
This study explores the innovative use of post-mining subsurface voids by proposing a coal mine goaf-based underground reservoir energy storage system. By fully utilizing the geothermal potential and insulation properties of the mined-out coal seam, we ...
Zhenyu Wang, Jiawei Tang, Zixu Hu, Qiang Guo, Haiqin Zhang, Kangning Zhang, Siwei Kang, Xiaolin He   +7 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

CLEAN WATER AND HOW TO GET IT. [PDF]

Journal of the American Chemical Society, 1907
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openaire   +2 more sources