Results 31 to 40 of about 337,488 (268)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Crystal structure of μ-oxido-bis{2,2-[ethylidene(bis-(nitrilomethylidyne))] diphenolato} iron(III), [Fe2O(C16H14N2)2]·2.5(C7H8), C49.50H48Fe2N4O5

Zeitschrift für Kristallographie - New Crystal Structures, 2012
C49.50H48Fe2N4O5, monoclinic, P21/c (no. 14), a = 12.7141(9) Å, b = 16.559(1) Å, c = 21.164(2) Å, β = 100.628(1)°, V = 4379.4 Å3, Z = 4, Rgt(F) = 0.0624, wRref(F2) = 0.1592, T = 187 K.
Li Liang-Zhao, Song Guo-Lin, Tang Guo-Yi
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

N2O and NO Emissions from CFBC Cofiring Dried Sewage Sludge, Wet Sewage Sludge with Coal and PE

Journal of Combustion, 2013
Experiments on cofiring dried sewage sludge, wet sewage sludge with coal and polyethylene (PE) were carried out on a pilot scale 0.15MWt circulating fluidized bed combustion (CFBC) plant, and the influence of furnace temperatures, cofiring rates on N2O ...
Zhiwei Li, Hongzhou He
doaj   +1 more source

Calibration and performance evaluation of PM_2.5 and NO₂ air quality sensors for environmental epidemiology [PDF]

Atmospheric Measurement Techniques
Over the past few decades, the study and the use of air quality sensors have significantly increased, leading to a wealth of experience and a deeper understanding of their strengths and limitations.
M. Chacón-Mateos, M. Chacón-Mateos, H. García-Salamero, B. Laquai, U. Vogt   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Optimal design of liquid cooling structures for superfast charging cable cores under a high current load

Case Studies in Thermal Engineering
Superchargers have become a focus of much research into new-energy vehicles, for which the cooling of high-current cable cores is a key problem that needs to be solved.
Yue Wu, He Yu, Jinhao Zhang, Xixia Xu, Ruoyu Dai, Wenzhi Liu, He Lv, Yiming Xu, Qinfeng Wang, Hongzhou He, Jieqing Zheng   +10 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

In Situ Synthesis of CoMoO₄ Microsphere@rGO as a Matrix for High-Performance Li-S Batteries at Room and Low Temperatures

Molecules
Lithium–sulfur batteries (Li-S batteries) have attracted wide attention due to their high theoretical energy density and the low cost of sulfur cathode material.
Ronggang Zhang, Haiji Xiong, Jia Liang, Jinwei Yan, Dingrong Deng, Yi Li, Qihui Wu   +6 more
doaj   +1 more source