Results 51 to 60 of about 321,393 (268)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Establishment of UPLC-Q-TOF-MS Fingerprints and Antioxidant Spectroscopic Relationship of Ethanol-eluting Sites of Tetrastigma hemsleyanum Macroporous Resin

Shipin gongye ke-ji
Objective: To study the spectrum-effect relationship between the extracts of Tetrastigma hemsleyanum and its antioxidant activity, and to clarify the quality markers of its antioxidant activity.
Guoqiang CAI, Zhijie XU, Xiaohong QIAO, Tianji LUO, Lei ZHANG, Yibo HE   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Electrochemical Preparation of Sub-micrometer Sn-Sb Alloy powder in ChCl-EG deep eutectic solvent

International Journal of Electrochemical Science, 2016
The sub-micrometer Sn-Sb alloy powders were electrochemically prepared on a titanium substrate in choline chloride-ethylene glycol (ChCl-EG, 1:2 molar ratio) deep eutectic solvent containing 0.2 M SbCl3 and 0.2 M SnCl2.
Zhaolei Su, Cunying Xu, Yixin Hua, Jian Li, Juanjian Ru, Mengmeng Wang, Li Xiong, Yadong Zhang   +7 more
doaj   +3 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Output risk evolution analysis of agricultural non-point source pollution under different scenarios based on multi-model

Global Ecology and Conservation, 2020
The Fuling District is located in central Chongqing, China, and characterized by a high ecological status, a high ecological risk, a high agricultural proportion in economy, and a high agricultural non-point source pollution (AGNPS) risk, and represents ...
Kang-Wen Zhu, Yu-Cheng Chen, Sheng Zhang, Zhi-Min Yang, Lei Huang, Lei Li, Bo Lei, Zhong-Bo Zhou, Hai-Ling Xiong, Xi-Xi Li, Yue-Chen Li, Shahidul Islam   +11 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Symmetrization in Clean and Nil-Clean Rings

Izvestiya of Saratov University. New Series. Series: Mathematics. Mechanics. Informatics, 2020
A ring \(R\) is said to be \textsl{double nil-clean} or just \textsl{ D-nil-clean} for short if, for every \(a\in R\), there exists \(e\in (aRa)\cap Id(R)\) such that \(a=e+q\) for some \(q\in \mathrm{Nil}(R)\). Similarly, a ring \(R\) is said to be \textsl{double clean} or just \textsl{D-clean} for short if, for each \(a\in R\), there exists \(e\in ...
openaire   +2 more sources