Results 61 to 70 of about 1,549,242 (288)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Formation and Application of High Reflectivity Controllable Barium Sulfate Microspheres

Crystals, 2018
This paper investigated the influence of reaction conditions on particle morphology. X-ray powder diffraction (XRD), particle size distribution (PSD), and scanning electron microscopy (SEM) were used to characterize the morphology of barium sulfate.
Yuejiao Liu, Xiaoyan Guo, Qingyang Gu, Guangxiang He, Suohe Yang, Haibo Jin   +5 more
doaj   +1 more source

Vegetation of the water-level fluctuation zone in the Three Gorges Reservoir at the initial impoundment stage

Global Ecology and Conservation, 2020
The water-level of Three Gorges Reservoir first reached a normal storage level 175 m in October 2010, resulting in a large-area water-fluctuating zone with an elevation difference of 30 m (145–175 m).
Kang-wen Zhu, Yu-cheng Chen, Sheng Zhang, Bo Lei, Zhi-min Yang, Lei Huang   +5 more
doaj   +1 more source

Mechanical cleaning of graphene

, 2011
Contamination of graphene due to residues from nanofabrication often introduces background doping and reduces charge carrier mobility. For samples of high electronic quality, post-lithography cleaning treatments are therefore needed.
Barreiro, A., Calado, V. E., Goossens, A. M., Taniguchi, T., Vandersypen, L. M. K., Watanabe, K.   +5 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Establishment of UPLC-Q-TOF-MS Fingerprints and Antioxidant Spectroscopic Relationship of Ethanol-eluting Sites of Tetrastigma hemsleyanum Macroporous Resin

Shipin gongye ke-ji
Objective: To study the spectrum-effect relationship between the extracts of Tetrastigma hemsleyanum and its antioxidant activity, and to clarify the quality markers of its antioxidant activity.
Guoqiang CAI, Zhijie XU, Xiaohong QIAO, Tianji LUO, Lei ZHANG, Yibo HE   +5 more
doaj   +1 more source

Identification and prevention of agricultural non-point source pollution risk based on the minimum cumulative resistance model

Global Ecology and Conservation, 2020
Agricultural non-point source pollution (AGNPS) risk prevention and control is more conducive to reducing costs than post-treatment. Therefore, how to effectively identify risks is a key problem to be solved. The study area is located in the NANTUO small
Kang-wen Zhu, Yu-cheng Chen, Sheng Zhang, Zhi-min Yang, Lei Huang, Bo Lei, Lei Li, Zhong-bo Zhou, Hai-ling Xiong, Xi-xi Li   +9 more
doaj   +1 more source

Water Consumption in the Automatic Milking Systems

Acta Technologica Agriculturae, 2021
The article deals with the determination of water consumption at selected dairy farms during milking using automatic milking systems (AMS). The aim was to determine the water consumption during basic activities associated with the AMS use, namely water ...
Vaculík Petr, Jehlička Tomáš, Kažimírová Viera, Smejtková Andrea   +3 more
doaj   +1 more source

Brush cleaning to remove fungal spores from seed lots [PDF]

, 2005
Common bunt is infecting wheat seedling just after sowing, in the heterotrophic phase before seedling emergence. The seed per se is healthy at the time of sowing, but gets infected from spores resting on the seed surface. Bechel et al.
Borgen, Anders
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source