Results 61 to 70 of about 14,551 (299)

Understanding the effectiveness of attachments in clear aligner therapy: navigating design, placement, material selection and biomechanics

open access: yesAustralasian Orthodontic Journal
Clear aligner treatments have gained popularity due to their aesthetic advantages over traditional metal brackets. Attachments play a crucial role in enhancing the efficacy of treatment by addressing challenges posed by the flexibility of aligner ...
Demir Gizem Boztaş
doaj   +1 more source

Can esthetically pleasing aligners change the root morphologies? – A narrative review

open access: yesSRM Journal of Research in Dental Sciences
Background: The occurrence of root resorption (RR) is an unavoidable result of orthodontic treatment. Finding a straightforward approach to its prevention remains a challenge.
Shivika Garg   +5 more
doaj   +1 more source

Treatment of Deep Bite Using Clear Aligner Therapy [PDF]

open access: yes, 2023
Background: Deep bite is a type of malocclusion that can lead to problems with bite, mastication, speech, and has the potential to damage teeth and gums.
Zarei, Mahban, Zhou, Robert
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response. [PDF]

open access: yes, 2019
The progressive failure of protein homeostasis is a hallmark of aging and a common feature in neurodegenerative disease. As the enzymes executing the final stages of autophagy, lysosomal proteases are key contributors to the maintenance of protein ...
Ashrafi, Kaveh   +10 more
core   +1 more source

Underestimated effect of intragenic HIV-1 DNA methylation on viral transcription in infected individuals [PDF]

open access: yes, 2020
Background: The HIV-1 proviral genome harbors multiple CpG islands (CpGIs), both in the promoter and intragenic regions. DNA methylation in the promoter region has been shown to be heavily involved in HIV-1 latency regulation in cultured cells.
De Meyer, Tim   +7 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Does the need for refinement sets of orthodontic clear aligners correlate with professional experience? [PDF]

open access: yesDental Press Journal of Orthodontics
Objective: To assess how often orthodontists request additional aligners and correlate this need with professional’s experience. Methods: A questionnaire was sent by instant messaging app (WhatsApp) to 188 orthodontists who answered it voluntarily ...
Victor de Miranda LADEWIG   +6 more
doaj   +1 more source

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