Results 81 to 90 of about 4,057,216 (280)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Where is clear aligner therapy research heading?

Background and Aim: The aim of this study was tosystematically identify the core themes, research trends, andunderexplored topics in the clear aligner literature by employinga natural language processing-based topic modeling approachusing the BERTopic ...
Yavuz Selim Genç, Nurbanu Moroğlu, Ruşen Erdem, Ahmet Yıldırım, Burkay Moroğlu   +4 more
core   +1 more source

Evaluation of Awareness and Perception of Clear Aligner Orthodontic Treatment Among Students of Hawler Medical University.

Erbil Dental Journal
Background and Objectives: The growing emphasis on appearance has led to an increased   interest in orthodontic treatment among adults, particularly those who are highly self-conscious about their looks.
Maryam Fouad Bilal, Ahmed Qesim Ali, Layard Khalil Ibrahim   +2 more
doaj  

Microplastics in Clear Aligner Therapy: A Narrative Review

Oral Health Research and Clinical Evidence
An extensive acceptance of advancements in the realm of orthodontics has paved the way for the entry of a new generation of appliances, mainly clear aligners, to surpass the inconvenience caused by conventional traditional methods of orthodontic braces. These aligners, although have earned an esthetic compliance, has its own shortcomings.
B. Shivane Praba, Abinaya Somaskandhan
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Clear aligner therapy- contemporary knowledge

, 2020
Terapija prozirnim alignerima odnosi se na niz prozirnih, individualno izrađenih, mobilnih, plastičnih alignera koji pomiču zube u željeni položaj. Pomoću virtualnog 3D modela pacijentove gornje i donje čeljusti dobivenog skeniranjem modela ili usta ...
Martinčević, Toni
core   +1 more source

Does the need for refinement sets of orthodontic clear aligners correlate with professional experience? [PDF]

Dental Press Journal of Orthodontics
Objective: To assess how often orthodontists request additional aligners and correlate this need with professional’s experience. Methods: A questionnaire was sent by instant messaging app (WhatsApp) to 188 orthodontists who answered it voluntarily ...
Victor de Miranda LADEWIG, Kamila de Oliveira Novais MACHADO, Thaís Maria Freire FERNANDES, Renata Rodrigues de ALMEIDA-PEDRIN, Paula Vanessa Pedron OLTRAMARI, Márcio Rodrigues de ALMEIDA, Ana Cláudia de Castro Ferreira CONTI   +6 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Factors Affecting Attachment Loss in Clear Aligner Treatment: A Prospective Clinical Study

Bezmiâlem Science
Objective: This study aimed to evaluate the incidence of composite attachment loss in patients undergoing clear aligner treatment and to identify patient-, tooth-, and treatment-related factors associated with attachment debonding.
Şerife ŞAHİN, Hümeyra ÜNSAL, Gökmen KURT   +2 more
doaj   +1 more source