Results 91 to 100 of about 337,050 (372)

Metastatic Renal Cell Carcinoma in the Sinonasal Region [PDF]

, 2013
Sinonasal region is an exceptional site for metastatic tumors. Renal cell carcinoma is known to metastasise to the most unusual sites, the sinonasal region being one of them. Clear cell carcinoma is its most common histologic variant.
Mahantachar, V, Raj, JA, Rajaram, T
core   +1 more source

Evaluation of Clear Cell, Papillary, and Chromophobe Renal Cell Carcinoma Metastasis Sites and Association With Survival

JAMA Network Open, 2021
Key Points Question In metastatic renal cell carcinoma (RCC), do patterns of metastasis differ between histologic subtypes and are sites of metastasis associated with survival?
Shaan Dudani, G. de Velasco, J. Wells, C. Gan, F. Donskov, C. Porta, A. Fraccon, F. Pasini, J. Lee, A. Hansen, G. Bjarnason, B. Beuselinck, S. Pal, T. Yuasa, N. Kroeger, R. Kanesvaran, M. Reaume, C. Canil, T. Choueiri, D. Heng   +19 more
semanticscholar   +1 more source

Imaging the Clear Cell Renal Cell Carcinoma Proteome [PDF]

Journal of Urology, 2013
A key barrier to identifying tissue biomarkers of clear cell renal cell carcinoma is the heterogeneity of protein expression in tissue. However, by providing spectra for every 0.05 mm(2) area of tissue, imaging mass spectrometry reveals the spatial distribution of peptides.
Oluwole Fadare, Peter E. Clark, Richard M. Caprioli, Erin H. Seeley, Todd M. Morgan   +4 more
openaire   +2 more sources

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

A case of multilocular cystic renal cell carcinoma diagnosed by pharmacoangiography [PDF]

, 1994
A case of multilocular cystic renal cell carcinoma in a 62-year-old man was reported. He was admitted with complaint of asymptomatic gross hematuria. Abdominal ultrasonography and CT scan revealed multilocular cystic mass at the lower pole of the right ...
三木, 誠, 山本, 真也, 松本, 哲夫, 相澤, 卓, 鉾石, 文彦   +4 more
core  

FOXD1 regulates cell division in clear cell renal cell carcinoma

BMC Cancer, 2021
Background Forkhead transcription factors control cell growth in multiple cancer types. Foxd1 is essential for kidney development and mitochondrial metabolism, but its significance in renal cell carcinoma (ccRCC) has not been reported.
Kyle H. Bond, Jennifer L. Fetting, Christine W. Lary, Ivette F. Emery, Leif Oxburgh   +4 more
doaj   +1 more source

CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma

Cancer Discovery
CTX130, an allogeneic CD70-targeting CAR-T cell therapy, yielded disease control in the majority of patients with clear cell renal cell carcinoma treated in a phase I clinical trial, with one patient obtaining a durable complete remission.
S. Pal, B. Tran, J. Haanen, M. Hurwitz, A. Sacher, N. Tannir, L. Budde, Simon J Harrison, S. Klobuch, Sagar S Patel, Luis Meza, Mary-Lee Dequeant, Anna Ma, Q. A. He, Leah M Williams, A. Keegan, Ellen B Gurary, H. Dar, Sushant Karnik, Changan Guo, Heidi Heath, Rachel R Yuen, Phuong K Morrow, N. Agarwal, S. Srour   +24 more
semanticscholar   +1 more source

Antigenic targets in clear cell renal cell carcinoma

Kidney Cancer, 2023
Immune checkpoint inhibitors (ICIs) have transformed the management of advanced renal cell carcinoma (RCC), but most patients still do not receive a long-term benefit from these therapies, and many experience off-target, immune-related adverse effects. RCC is also different from many other ICI-responsive tumors, as it has only a modest mutation burden,
Schindler, Nicholas R., Braun, David A.
openaire   +2 more sources

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

腎細胞癌の膵転移の1例 [PDF]

, 1990
A case of asynchronous bilateral renal cell carcinoma with pancreatic metastasis is described. Left nephrectomy and tumorectomy in the right kidney were performed.
Gohji, Kazuo, Kamidono, Sadao, Matsumoto, Osamu   +2 more
core