Survival Outcomes in Older Adults With Axial Spondyloarthritis and Concomitant Cancer
Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman +7 more
wiley +1 more source
Surgical excision of renal cell carcinoma with caval and intra-atrial tumour thrombus extension using deep hypothermic circulatory arrest [PDF]
Surgery for tumour thrombus extension in Renal Cell Carcinoma may be associated with a good prognosis if no distant metastases are identified and if the thrombus can be completely excised.
Bugeja, Simon +3 more
core
Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling [PDF]
BACKGROUND: Proteomics-based approaches for biomarker discovery are promising strategies used in cancer research. We present state-of-art label-free quantitative proteomics method to assess proteome of renal cell carcinoma (RCC) compared with noncancer ...
J T-J Huang +26 more
core +1 more source
An Overview of Epigenetics in Clear Cell Renal Cell Carcinoma
Renal cell carcinoma (RCC) represents a heterogenous group of cancers with complex genetic background and histological varieties, which require various clinical therapies. Clear cell RCC represents the most common form of RCC that accounts for 3 out of 4 RCC cases.
STAMATIKI GRAMMATIKAKI +7 more
openaire +3 more sources
Objective Existing patient‐reported outcome (PRO) measures for systemic sclerosis (SSc) have important limitations, including inadequate coverage of early disease and limited inclusion of diffuse cutaneous (dcSSc) and limited cutaneous (lcSSc) subtypes.
George J. Greene +5 more
wiley +1 more source
Resistance after chronic application of the HDAC-inhibitor valproic acid is associated with elevated Akt activation in renal cell carcinoma in vivo [PDF]
Targeted drugs have significantly improved the therapeutic options for advanced renal cell carcinoma (RCC). However, resistance often develops, negating the benefit of these agents.
Eva Juengel +20 more
core +2 more sources
Clear Cell Renal Cell Carcinoma with a Ureteral Thrombus [PDF]
Introduction: Cancers of the kidney, arising from either the renal parenchymal tissue or the renal pelvis, is among the 13 commonest types of malignancy globally, accounting for between 3% and 4% of all newly diagnosed cancers. Renal cell carcinoma (RCC) accounts for 85% of all malignant renal neoplasms.
John, Jeff +3 more
openaire +2 more sources
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
alpha B-Crystallin in clear cell renal cell carcinoma: Tumor progression and prognostic significance
Objectives: AlphaB-crystallin (alpha B-crystallin), a small heat shock protein, has been reported to be involved in the growth, antiapoptosis, migration, and chemoresistance of human malignancies.
Ho, Pei-Yin;Chueh, Shih-Chieh;Chiou, Shyh-Horng;Wang, Shuo-Meng;Lin, Wei-Chou;Lee, I-Liang;Yang, Hsin-Yi;Peng, Hsiang-Chi;Lai, Ming-Kuen +1 more
core +1 more source
Introduction Clear cell papillary renal cell carcinoma often develops in the context of the dialyzed kidney (end‐stage renal disease). However, the relationship between clear cell papillary renal cell carcinoma and microRNA expression in patients with ...
Ei Shiomi +11 more
doaj +1 more source

